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4n5u
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==Crystal structure of the 4th FN3 domain of human Protein Tyrosine phosphatase, receptor type F [PSI-NYSGRC-006240]== | ==Crystal structure of the 4th FN3 domain of human Protein Tyrosine phosphatase, receptor type F [PSI-NYSGRC-006240]== | ||
| - | <StructureSection load='4n5u' size='340' side='right' caption='[[4n5u]], [[Resolution|resolution]] 1.46Å' scene=''> | + | <StructureSection load='4n5u' size='340' side='right'caption='[[4n5u]], [[Resolution|resolution]] 1.46Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4n5u]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4n5u]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N5U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4N5U FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.456Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | <tr id=' | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4n5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n5u OCA], [https://pdbe.org/4n5u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4n5u RCSB], [https://www.ebi.ac.uk/pdbsum/4n5u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4n5u ProSAT]</span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/PTPRF_HUMAN PTPRF_HUMAN] Possible cell adhesion receptor. It possesses an intrinsic protein tyrosine phosphatase activity (PTPase).<ref>PMID:10338209</ref> The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one.<ref>PMID:10338209</ref> |
| + | |||
| + | ==See Also== | ||
| + | *[[Tyrosine phosphatase 3D structures|Tyrosine phosphatase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Almo | + | [[Category: Almo SC]] |
| - | [[Category: Attonito | + | [[Category: Attonito J]] |
| - | [[Category: Banu | + | [[Category: Banu R]] |
| - | [[Category: Bhosle | + | [[Category: Bhosle R]] |
| - | [[Category: Calarese | + | [[Category: Calarese DA]] |
| - | [[Category: Casadevall | + | [[Category: Casadevall A]] |
| - | [[Category: Celikgil | + | [[Category: Celikgil A]] |
| - | [[Category: Chamala | + | [[Category: Chamala S]] |
| - | [[Category: Chan | + | [[Category: Chan MK]] |
| - | [[Category: Chowdhury | + | [[Category: Chowdhury S]] |
| - | [[Category: Fiser | + | [[Category: Fiser A]] |
| - | [[Category: Garforth | + | [[Category: Garforth SJ]] |
| - | [[Category: Glenn | + | [[Category: Glenn AS]] |
| - | [[Category: Hillerich | + | [[Category: Hillerich B]] |
| - | + | [[Category: Khafizov K]] | |
| - | [[Category: Khafizov | + | [[Category: Kumar PR]] |
| - | [[Category: Kumar | + | [[Category: Love JD]] |
| - | [[Category: Love | + | [[Category: Patel H]] |
| - | + | [[Category: Patel R]] | |
| - | [[Category: Patel | + | [[Category: Seidel RD]] |
| - | [[Category: Patel | + | [[Category: Smith B]] |
| - | [[Category: Seidel | + | [[Category: Stead M]] |
| - | [[Category: Smith | + | [[Category: Toro R]] |
| - | [[Category: Stead | + | |
| - | [[Category: Toro | + | |
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Crystal structure of the 4th FN3 domain of human Protein Tyrosine phosphatase, receptor type F [PSI-NYSGRC-006240]
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Categories: Homo sapiens | Large Structures | Almo SC | Attonito J | Banu R | Bhosle R | Calarese DA | Casadevall A | Celikgil A | Chamala S | Chan MK | Chowdhury S | Fiser A | Garforth SJ | Glenn AS | Hillerich B | Khafizov K | Kumar PR | Love JD | Patel H | Patel R | Seidel RD | Smith B | Stead M | Toro R
