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4n68

From Proteopedia

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{{STRUCTURE_4n68| PDB=4n68 | SCENE= }}
 
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===Crystal structure of an internal FN3 domain from human Contactin-5 [PSI-NYSGRC-005804]===
 
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==Function==
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==Crystal structure of an internal FN3 domain from human Contactin-5 [PSI-NYSGRC-005804]==
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[[http://www.uniprot.org/uniprot/CNTN5_HUMAN CNTN5_HUMAN]] Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity in the cerebral cortical neurons but not in hippocampal neurons. Probably involved in neuronal activity in the auditory system (By similarity).
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<StructureSection load='4n68' size='340' side='right'caption='[[4n68]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[4n68]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N68 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4N68 FirstGlance]. <br>
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[[4n68]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N68 OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4n68 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n68 OCA], [https://pdbe.org/4n68 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4n68 RCSB], [https://www.ebi.ac.uk/pdbsum/4n68 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4n68 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CNTN5_HUMAN CNTN5_HUMAN] Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity in the cerebral cortical neurons but not in hippocampal neurons. Probably involved in neuronal activity in the auditory system (By similarity).
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Almo, S C.]]
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[[Category: Large Structures]]
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[[Category: Attonito, J.]]
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[[Category: Almo SC]]
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[[Category: Banu, R.]]
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[[Category: Attonito J]]
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[[Category: Bhosle, R.]]
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[[Category: Banu R]]
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[[Category: Calarese, D A.]]
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[[Category: Bhosle R]]
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[[Category: Casadevall, A.]]
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[[Category: Calarese DA]]
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[[Category: Celikgil, A.]]
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[[Category: Casadevall A]]
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[[Category: Chamala, S.]]
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[[Category: Celikgil A]]
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[[Category: Chan, M K.]]
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[[Category: Chamala S]]
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[[Category: Chowdhury, S.]]
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[[Category: Chan MK]]
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[[Category: Fiser, A.]]
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[[Category: Chowdhury S]]
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[[Category: Garforth, S J.]]
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[[Category: Fiser A]]
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[[Category: Glenn, A S.]]
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[[Category: Garforth SJ]]
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[[Category: Hillerich, B.]]
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[[Category: Glenn AS]]
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[[Category: IFN, Atoms-to-Animals:.The Immune Function Network.]]
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[[Category: Hillerich B]]
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[[Category: Khafizov, K.]]
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[[Category: Khafizov K]]
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[[Category: Kumar, P R.]]
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[[Category: Kumar PR]]
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[[Category: Love, J D.]]
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[[Category: Love JD]]
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[[Category: NYSGRC, New York Structural Genomics Research Consortium.]]
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[[Category: Patel H]]
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[[Category: Patel, H.]]
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[[Category: Patel R]]
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[[Category: Patel, R.]]
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[[Category: Seidel RD]]
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[[Category: Seidel, R D.]]
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[[Category: Smith B]]
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[[Category: Smith, B.]]
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[[Category: Stead M]]
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[[Category: Stead, M.]]
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[[Category: Toro R]]
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[[Category: Toro, R.]]
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[[Category: Cell adhesion]]
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[[Category: Internal fn3 domain]]
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[[Category: New york structural genomics research consortium]]
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[[Category: Nysgrc]]
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[[Category: Psi-biology]]
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[[Category: Structural genomic]]
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Current revision

Crystal structure of an internal FN3 domain from human Contactin-5 [PSI-NYSGRC-005804]

PDB ID 4n68

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