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4n6l

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==Crystal structure of human cystatin E/M==
==Crystal structure of human cystatin E/M==
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<StructureSection load='4n6l' size='340' side='right' caption='[[4n6l]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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<StructureSection load='4n6l' size='340' side='right'caption='[[4n6l]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4n6l]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N6L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4N6L FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4n6l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N6L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4N6L FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4n6m|4n6m]], [[4n6n|4n6n]], [[4n6o|4n6o]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.952&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4n6l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n6l OCA], [http://pdbe.org/4n6l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4n6l RCSB], [http://www.ebi.ac.uk/pdbsum/4n6l PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4n6l ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4n6l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n6l OCA], [https://pdbe.org/4n6l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4n6l RCSB], [https://www.ebi.ac.uk/pdbsum/4n6l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4n6l ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CYTM_HUMAN CYTM_HUMAN]] Shows moderate inhibition of cathepsin B but is not active against cathepsin C.
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[https://www.uniprot.org/uniprot/CYTM_HUMAN CYTM_HUMAN] Shows moderate inhibition of cathepsin B but is not active against cathepsin C.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Brandstetter, H]]
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[[Category: Homo sapiens]]
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[[Category: Dall, E]]
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[[Category: Large Structures]]
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[[Category: Asparaginyl endopeptidase]]
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[[Category: Brandstetter H]]
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[[Category: Cancer]]
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[[Category: Dall E]]
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[[Category: Cathepsin]]
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[[Category: Cystatin fold]]
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[[Category: Cysteine protease inhibitor]]
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[[Category: Hydrolase inhibitor]]
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[[Category: Legumain]]
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[[Category: Papain]]
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[[Category: Protease inhibitor]]
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[[Category: Reactive center loop]]
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Current revision

Crystal structure of human cystatin E/M

PDB ID 4n6l

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