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4nof

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{{STRUCTURE_4nof| PDB=4nof | SCENE= }}
 
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===Crystal structure of the second Ig domain from mouse Polymeric Immunoglobulin receptor [PSI-NYSGRC-006220]===
 
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==Function==
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==Crystal structure of the second Ig domain from mouse Polymeric Immunoglobulin receptor [PSI-NYSGRC-006220]==
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[[http://www.uniprot.org/uniprot/PIGR_MOUSE PIGR_MOUSE]] This receptor binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment (By similarity).
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<StructureSection load='4nof' size='340' side='right'caption='[[4nof]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[4nof]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NOF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NOF FirstGlance]. <br>
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[[4nof]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NOF OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
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[[Category: Ahmed, M.]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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[[Category: Almo, S C.]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nof FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nof OCA], [https://pdbe.org/4nof PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nof RCSB], [https://www.ebi.ac.uk/pdbsum/4nof PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nof ProSAT]</span></td></tr>
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[[Category: Attonito, J.]]
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</table>
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[[Category: Banu, R.]]
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== Function ==
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[[Category: Bhosle, R.]]
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[https://www.uniprot.org/uniprot/PIGR_MOUSE PIGR_MOUSE] This receptor binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment (By similarity).
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[[Category: Calarese, D A.]]
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__TOC__
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[[Category: Casadevall, A.]]
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</StructureSection>
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[[Category: Celikgil, A.]]
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[[Category: Large Structures]]
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[[Category: Chamala, S.]]
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[[Category: Mus musculus]]
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[[Category: Chan, M K.]]
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[[Category: Ahmed M]]
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[[Category: Chowdhury, S.]]
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[[Category: Almo SC]]
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[[Category: Fiser, A.]]
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[[Category: Attonito J]]
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[[Category: Garforth, S J.]]
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[[Category: Banu R]]
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[[Category: Glenn, A S.]]
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[[Category: Bhosle R]]
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[[Category: Hillerich, B.]]
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[[Category: Calarese DA]]
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[[Category: IFN, Atoms-to-Animals:.The Immune Function Network.]]
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[[Category: Casadevall A]]
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[[Category: Khafizov, K.]]
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[[Category: Celikgil A]]
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[[Category: Kumar, P R.]]
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[[Category: Chamala S]]
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[[Category: Love, J D.]]
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[[Category: Chan MK]]
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[[Category: NYSGRC, New York Structural Genomics Research Consortium.]]
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[[Category: Chowdhury S]]
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[[Category: Patel, H.]]
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[[Category: Fiser A]]
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[[Category: Patel, R.]]
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[[Category: Garforth SJ]]
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[[Category: Sampathkumar, P.]]
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[[Category: Glenn AS]]
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[[Category: Seidel, R D.]]
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[[Category: Hillerich B]]
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[[Category: Smith, B.]]
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[[Category: Khafizov K]]
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[[Category: Stead, M.]]
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[[Category: Kumar PR]]
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[[Category: Ifn]]
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[[Category: Love JD]]
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[[Category: Ig domain]]
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[[Category: Patel H]]
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[[Category: Immune function network]]
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[[Category: Patel R]]
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[[Category: Immune system]]
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[[Category: Sampathkumar P]]
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[[Category: New york structural genomics research consortium]]
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[[Category: Seidel RD]]
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[[Category: Nysgrc]]
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[[Category: Smith B]]
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[[Category: Ortholog]]
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[[Category: Stead M]]
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[[Category: Polymeric immunoglobulin receptor]]
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[[Category: Psi-biology]]
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[[Category: Structural genomic]]
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Current revision

Crystal structure of the second Ig domain from mouse Polymeric Immunoglobulin receptor [PSI-NYSGRC-006220]

PDB ID 4nof

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