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4nra

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==Crystal Structure of the bromodomain of human BAZ2B in complex with compound-6 E11322==
==Crystal Structure of the bromodomain of human BAZ2B in complex with compound-6 E11322==
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<StructureSection load='4nra' size='340' side='right' caption='[[4nra]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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<StructureSection load='4nra' size='340' side='right'caption='[[4nra]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4nra]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NRA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NRA FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4nra]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NRA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NRA FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2LW:1-(8-CHLORO-1,3,4,5-TETRAHYDRO-2H-PYRIDO[4,3-B]INDOL-2-YL)ETHANONE'>2LW</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4nr9|4nr9]], [[4nrb|4nrb]], [[4nrc|4nrc]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2LW:1-(8-CHLORO-1,3,4,5-TETRAHYDRO-2H-PYRIDO[4,3-B]INDOL-2-YL)ETHANONE'>2LW</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BAZ2B, KIAA1476 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nra FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nra OCA], [https://pdbe.org/4nra PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nra RCSB], [https://www.ebi.ac.uk/pdbsum/4nra PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nra ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nra FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nra OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4nra RCSB], [http://www.ebi.ac.uk/pdbsum/4nra PDBsum]</span></td></tr>
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</table>
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<table>
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== Function ==
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[https://www.uniprot.org/uniprot/BAZ2B_HUMAN BAZ2B_HUMAN] May play a role in transcriptional regulation interacting with ISWI.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4nra" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Bromodomain adjacent to zinc finger 3D structures|Bromodomain adjacent to zinc finger 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Arrowsmith, C H.]]
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[[Category: Large Structures]]
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[[Category: Bountra, C.]]
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[[Category: Arrowsmith CH]]
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[[Category: Chaikuad, A.]]
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[[Category: Bountra C]]
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[[Category: Delft, F von.]]
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[[Category: Chaikuad A]]
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[[Category: Edwards, A M.]]
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[[Category: Edwards AM]]
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[[Category: Fedorov, O.]]
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[[Category: Fedorov O]]
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[[Category: Felletar, I.]]
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[[Category: Felletar I]]
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[[Category: Ferguson, F M.]]
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[[Category: Ferguson FM]]
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[[Category: Filippakopoulos, P.]]
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[[Category: Filippakopoulos P]]
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[[Category: Knapp, S.]]
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[[Category: Knapp S]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Von Delft F]]
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[[Category: Acetylated lysine binding protein]]
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[[Category: Bromodomain]]
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[[Category: Kiaa1476]]
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[[Category: Sgc]]
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[[Category: Structural genomics consortium]]
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[[Category: Transcription]]
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[[Category: Walp4]]
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Current revision

Crystal Structure of the bromodomain of human BAZ2B in complex with compound-6 E11322

PDB ID 4nra

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