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4ot4

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==X-ray Structure of the Adduct formed between cisplatin and Ribonuclease A==
==X-ray Structure of the Adduct formed between cisplatin and Ribonuclease A==
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<StructureSection load='4ot4' size='340' side='right' caption='[[4ot4]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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<StructureSection load='4ot4' size='340' side='right'caption='[[4ot4]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4ot4]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OT4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OT4 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4ot4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OT4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OT4 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CPT:CISPLATIN'>CPT</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1jvt|1jvt]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CPT:CISPLATIN'>CPT</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pancreatic_ribonuclease Pancreatic ribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.27.5 3.1.27.5] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ot4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ot4 OCA], [https://pdbe.org/4ot4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ot4 RCSB], [https://www.ebi.ac.uk/pdbsum/4ot4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ot4 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ot4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ot4 OCA], [http://pdbe.org/4ot4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ot4 RCSB], [http://www.ebi.ac.uk/pdbsum/4ot4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ot4 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RNAS1_BOVIN RNAS1_BOVIN]] Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single stranded and double stranded RNA.<ref>PMID:7479688</ref>
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[https://www.uniprot.org/uniprot/RNAS1_BOVIN RNAS1_BOVIN] Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single stranded and double stranded RNA.<ref>PMID:7479688</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[Ribonuclease|Ribonuclease]]
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*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Pancreatic ribonuclease]]
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[[Category: Bos taurus]]
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[[Category: Merlino, A]]
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[[Category: Large Structures]]
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[[Category: Messori, L]]
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[[Category: Merlino A]]
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[[Category: Hydrolase]]
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[[Category: Messori L]]
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[[Category: Rnase a fold]]
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X-ray Structure of the Adduct formed between cisplatin and Ribonuclease A

PDB ID 4ot4

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