4qm1

<StructureSection load='4qm1' size='340' side='right' caption='[[4qm1]], [[Resolution|resolution]] 2.80&Aring;' scene=''>

<table><tr><td colspan='2'>[[4qm1]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_cereus_var._anthracis"_(cohn_1872)_smith_et_al._1946 "bacillus cereus var. anthracis" (cohn 1872) smith et al. 1946]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4mxs 4mxs]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QM1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QM1 FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=39H:2-(3-METHYL-4-OXO-3,4-DIHYDROPHTHALAZIN-1-YL)-N-(6,7,8,9-TETRAHYDRODIBENZO[B,D]FURAN-2-YL)ACETAMIDE'>39H</scene>, <scene name='pdbligand=IMP:INOSINIC+ACID'>IMP</scene></td></tr>

<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/IMP_dehydrogenase IMP dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.205 1.1.1.205] </span></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qm1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qm1 OCA], [http://pdbe.org/4qm1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4qm1 RCSB], [http://www.ebi.ac.uk/pdbsum/4qm1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4qm1 ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/Q81W29_BACAN Q81W29_BACAN]] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity).[HAMAP-Rule:MF_01964]

[[Category: IMP dehydrogenase]]

[[Category: Anderson, W F]]

[[Category: Structural genomic]]

[[Category: Csgid]]

[[Category: Gollapalli, D]]

[[Category: Gorla, S K]]

[[Category: Gu, M]]

[[Category: Hedstrom, L]]

[[Category: Joachimiak, A]]

[[Category: Kim, Y]]

[[Category: Makowska-Grzyska, M]]

[[Category: Mandapati, K]]

[[Category: Zhang, M]]

[[Category: Tim barrel]]