This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4qog

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (17:34, 20 September 2023) (edit) (undo)
 
(3 intermediate revisions not shown.)
Line 1: Line 1:
 +
==Crystal structure of fad quinone reductase 2 in complex with melatonin at 1.4A==
==Crystal structure of fad quinone reductase 2 in complex with melatonin at 1.4A==
-
<StructureSection load='4qog' size='340' side='right' caption='[[4qog]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
+
<StructureSection load='4qog' size='340' side='right'caption='[[4qog]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4qog]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QOG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QOG FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4qog]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QOG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QOG FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=ML1:N-[2-(5-METHOXY-1H-INDOL-3-YL)ETHYL]ACETAMIDE'>ML1</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4qod|4qod]], [[4qoe|4qoe]], [[4qof|4qof]], [[4qoh|4qoh]], [[4qoi|4qoi]], [[4qoj|4qoj]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=ML1:N-[2-(5-METHOXY-1H-INDOL-3-YL)ETHYL]ACETAMIDE'>ML1</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ribosyldihydronicotinamide_dehydrogenase_(quinone) Ribosyldihydronicotinamide dehydrogenase (quinone)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.10.99.2 1.10.99.2] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qog FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qog OCA], [https://pdbe.org/4qog PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qog RCSB], [https://www.ebi.ac.uk/pdbsum/4qog PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qog ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qog FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qog OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qog RCSB], [http://www.ebi.ac.uk/pdbsum/4qog PDBsum]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/NQO2_HUMAN NQO2_HUMAN]] The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.<ref>PMID:18254726</ref>
+
[https://www.uniprot.org/uniprot/NQO2_HUMAN NQO2_HUMAN] The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.<ref>PMID:18254726</ref>
 +
 
 +
==See Also==
 +
*[[Quinone reductase|Quinone reductase]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Antoine, M]]
+
[[Category: Homo sapiens]]
-
[[Category: Boutin, J A]]
+
[[Category: Large Structures]]
-
[[Category: Ferry, G]]
+
[[Category: Antoine M]]
-
[[Category: Isabet, T]]
+
[[Category: Boutin JA]]
-
[[Category: Serriere, J]]
+
[[Category: Ferry G]]
-
[[Category: Fad melatonin]]
+
[[Category: Isabet T]]
-
[[Category: Oxidoreductase]]
+
[[Category: Serriere J]]
-
[[Category: Oxidoreductase flavoprotein]]
+

Current revision

Crystal structure of fad quinone reductase 2 in complex with melatonin at 1.4A

PDB ID 4qog

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4qog"
Personal tools