This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4qza

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (17:41, 20 September 2023) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
==Mouse Tdt in complex with a DSB substrate, C-C base pair==
==Mouse Tdt in complex with a DSB substrate, C-C base pair==
-
<StructureSection load='4qza' size='340' side='right' caption='[[4qza]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
+
<StructureSection load='4qza' size='340' side='right'caption='[[4qza]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4qza]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QZA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QZA FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4qza]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QZA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QZA FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DCT:2,3-DIDEOXYCYTIDINE+5-TRIPHOSPHATE'>DCT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4i27|4i27]], [[1jms|1jms]], [[4qz8|4qz8]], [[4qz9|4qz9]], [[4qzb|4qzb]], [[4qzc|4qzc]], [[4qzd|4qzd]], [[4qze|4qze]], [[4qzf|4qzf]], [[4qzg|4qzg]], [[4qzh|4qzh]], [[4qzi|4qzi]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DCT:2,3-DIDEOXYCYTIDINE+5-TRIPHOSPHATE'>DCT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_nucleotidylexotransferase DNA nucleotidylexotransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.31 2.7.7.31] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qza FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qza OCA], [https://pdbe.org/4qza PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qza RCSB], [https://www.ebi.ac.uk/pdbsum/4qza PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qza ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qza FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qza OCA], [http://pdbe.org/4qza PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4qza RCSB], [http://www.ebi.ac.uk/pdbsum/4qza PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4qza ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/TDT_MOUSE TDT_MOUSE]] Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells.
+
[https://www.uniprot.org/uniprot/TDT_MOUSE TDT_MOUSE] Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 24: Line 23:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: DNA nucleotidylexotransferase]]
+
[[Category: Large Structures]]
-
[[Category: Delarue, M]]
+
[[Category: Mus musculus]]
-
[[Category: Gouge, J]]
+
[[Category: Delarue M]]
-
[[Category: Nucleus]]
+
[[Category: Gouge J]]
-
[[Category: Terminal deoxynucleotidyltransferase]]
+
-
[[Category: Transferase-dna complex]]
+

Current revision

Mouse Tdt in complex with a DSB substrate, C-C base pair

PDB ID 4qza

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4qza"
Personal tools