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4r88

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<StructureSection load='4r88' size='340' side='right'caption='[[4r88]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
<StructureSection load='4r88' size='340' side='right'caption='[[4r88]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4r88]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Klebsiella_pneumoniae_30660/njst258_1 Klebsiella pneumoniae 30660/njst258_1]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4jnr 4jnr]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R88 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4R88 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4r88]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae_30660/NJST258_1 Klebsiella pneumoniae 30660/NJST258_1]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4jnr 4jnr]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R88 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4R88 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1LD:5-FLUOROCYTOSINE'>1LD</scene>, <scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.952&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4r7w|4r7w]], [[4r85|4r85]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1LD:5-FLUOROCYTOSINE'>1LD</scene>, <scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">KPNJ1_03949 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1420012 Klebsiella pneumoniae 30660/NJST258_1])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4r88 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r88 OCA], [https://pdbe.org/4r88 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4r88 RCSB], [https://www.ebi.ac.uk/pdbsum/4r88 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4r88 ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cytosine_deaminase Cytosine deaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.4.1 3.5.4.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4r88 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r88 OCA], [http://pdbe.org/4r88 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4r88 RCSB], [http://www.ebi.ac.uk/pdbsum/4r88 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4r88 ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/A0A0E1CHI1_KLEPN A0A0E1CHI1_KLEPN]
==See Also==
==See Also==
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*[[Deaminase|Deaminase]]
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*[[Deaminase 3D structures|Deaminase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Cytosine deaminase]]
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[[Category: Klebsiella pneumoniae 30660/NJST258_1]]
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[[Category: Klebsiella pneumoniae 30660/njst258_1]]
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[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Almo, S C]]
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[[Category: Almo SC]]
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[[Category: Fedorov, A A]]
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[[Category: Fedorov AA]]
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[[Category: Fedorov, E V]]
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[[Category: Fedorov EV]]
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[[Category: Hitchcock, D S]]
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[[Category: Hitchcock DS]]
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[[Category: Raushel, F M]]
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[[Category: Raushel FM]]
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[[Category: 5-fluorocytosine]]
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[[Category: 5-methylcytosine deaminase]]
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[[Category: Amidohydrolase fold]]
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[[Category: Hydrolase]]
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Current revision

Crystal structure of 5-methylcytosine deaminase from Klebsiella pneumoniae liganded with 5-fluorocytosine

PDB ID 4r88

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