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4r8n
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==Crystal structure of Staphylococcal nuclease variant V23I/V66I/I72V/I92V at cryogenic temperature== | ==Crystal structure of Staphylococcal nuclease variant V23I/V66I/I72V/I92V at cryogenic temperature== | ||
| - | <StructureSection load='4r8n' size='340' side='right' caption='[[4r8n]], [[Resolution|resolution]] 1.65Å' scene=''> | + | <StructureSection load='4r8n' size='340' side='right'caption='[[4r8n]], [[Resolution|resolution]] 1.65Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4r8n]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R8N OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[4r8n]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R8N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4R8N FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=THP:THYMIDINE-3,5-DIPHOSPHATE'>THP</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=THP:THYMIDINE-3,5-DIPHOSPHATE'>THP</scene></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4r8n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r8n OCA], [https://pdbe.org/4r8n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4r8n RCSB], [https://www.ebi.ac.uk/pdbsum/4r8n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4r8n ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/NUC_STAAU NUC_STAAU] Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond. |
==See Also== | ==See Also== | ||
| - | *[[Staphylococcal nuclease|Staphylococcal nuclease]] | + | *[[Staphylococcal nuclease 3D structures|Staphylococcal nuclease 3D structures]] |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Caro | + | [[Category: Staphylococcus aureus]] |
| - | [[Category: Flores | + | [[Category: Caro JA]] |
| - | [[Category: Garcia-Moreno | + | [[Category: Flores E]] |
| - | [[Category: Heroux | + | [[Category: Garcia-Moreno EB]] |
| - | [[Category: Schlessman | + | [[Category: Heroux A]] |
| - | + | [[Category: Schlessman JL]] | |
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Current revision
Crystal structure of Staphylococcal nuclease variant V23I/V66I/I72V/I92V at cryogenic temperature
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