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4rkb

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==Crystal structure of Staphylococcal nuclease variant Delta+PHS V66T/V99T at cryogenic temperature==
==Crystal structure of Staphylococcal nuclease variant Delta+PHS V66T/V99T at cryogenic temperature==
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<StructureSection load='4rkb' size='340' side='right' caption='[[4rkb]], [[Resolution|resolution]] 1.88&Aring;' scene=''>
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<StructureSection load='4rkb' size='340' side='right'caption='[[4rkb]], [[Resolution|resolution]] 1.88&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4rkb]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RKB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RKB FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4rkb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RKB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RKB FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=THP:THYMIDINE-3,5-DIPHOSPHATE'>THP</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.88&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3bdc|3bdc]], [[4kjn|4kjn]], [[4k5v|4k5v]], [[4kjo|4kjo]], [[4miu|4miu]], [[4rkl|4rkl]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=THP:THYMIDINE-3,5-DIPHOSPHATE'>THP</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Micrococcal_nuclease Micrococcal nuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.31.1 3.1.31.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rkb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rkb OCA], [https://pdbe.org/4rkb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rkb RCSB], [https://www.ebi.ac.uk/pdbsum/4rkb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rkb ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rkb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rkb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4rkb RCSB], [http://www.ebi.ac.uk/pdbsum/4rkb PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/NUC_STAAW NUC_STAAW]] Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond (By similarity).
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[https://www.uniprot.org/uniprot/NUC_STAAU NUC_STAAU] Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond.
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==See Also==
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*[[Staphylococcal nuclease 3D structures|Staphylococcal nuclease 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Micrococcal nuclease]]
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[[Category: Large Structures]]
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[[Category: Caro, J A]]
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[[Category: Staphylococcus aureus]]
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[[Category: E., B Garcia-Moreno]]
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[[Category: Caro JA]]
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[[Category: Schlessman, J L]]
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[[Category: Garcia-Moreno E B]]
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[[Category: Cavity]]
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[[Category: Schlessman JL]]
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[[Category: Hydrolase]]
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[[Category: Hyperstable variant]]
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[[Category: Pdtp]]
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[[Category: Pressure]]
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[[Category: Staphylococcal nuclease]]
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Current revision

Crystal structure of Staphylococcal nuclease variant Delta+PHS V66T/V99T at cryogenic temperature

PDB ID 4rkb

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