This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4s20

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (18:01, 20 September 2023) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Large structure}}
+
 
==Structural basis for transcription reactivation by RapA==
==Structural basis for transcription reactivation by RapA==
-
<StructureSection load='4s20' size='340' side='right' caption='[[4s20]], [[Resolution|resolution]] 4.70&Aring;' scene=''>
+
<StructureSection load='4s20' size='340' side='right'caption='[[4s20]], [[Resolution|resolution]] 4.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4s20]] is a 16 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4S20 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4S20 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4s20]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4S20 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4S20 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 4.7&#8491;</td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_RNA_polymerase DNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.6 2.7.7.6] </span></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4s20 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4s20 OCA], [http://pdbe.org/4s20 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4s20 RCSB], [http://www.ebi.ac.uk/pdbsum/4s20 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4s20 ProSAT]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4s20 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4s20 OCA], [https://pdbe.org/4s20 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4s20 RCSB], [https://www.ebi.ac.uk/pdbsum/4s20 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4s20 ProSAT]</span></td></tr>
</table>
</table>
-
{{Large structure}}
 
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/K0BU55_ECO1E K0BU55_ECO1E]] Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.[HAMAP-Rule:MF_00366][SAAS:SAAS00054255] [[http://www.uniprot.org/uniprot/B1X6E7_ECODH B1X6E7_ECODH]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.[HAMAP-Rule:MF_00059] [[http://www.uniprot.org/uniprot/K0BCS5_ECO1E K0BCS5_ECO1E]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.[HAMAP-Rule:MF_01322][SAAS:SAAS00054030] [[http://www.uniprot.org/uniprot/K0AVA1_ECO1C K0AVA1_ECO1C]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.[HAMAP-Rule:MF_01321][RuleBase:RU000432] [[http://www.uniprot.org/uniprot/RAPA_ECOLI RAPA_ECOLI]] Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity).<ref>PMID:11751638</ref>
+
[https://www.uniprot.org/uniprot/RPOB_ECOLI RPOB_ECOLI] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.[HAMAP-Rule:MF_01321]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 22: Line 21:
==See Also==
==See Also==
-
*[[RNA polymerase|RNA polymerase]]
+
*[[Helicase 3D structures|Helicase 3D structures]]
 +
*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: DNA-directed RNA polymerase]]
+
[[Category: Escherichia coli]]
-
[[Category: Liu, B]]
+
[[Category: Large Structures]]
-
[[Category: Steitz, T A]]
+
[[Category: Liu B]]
-
[[Category: Zuo, Y]]
+
[[Category: Steitz TA]]
-
[[Category: Atpase]]
+
[[Category: Zuo Y]]
-
[[Category: Dna translocase]]
+
-
[[Category: Dna-directed rna polymerase]]
+
-
[[Category: Transcription transferase]]
+
-
[[Category: Transferase-dna-rna complex]]
+

Current revision

Structural basis for transcription reactivation by RapA

PDB ID 4s20

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4s20"
Personal tools