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4s2q
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of HMG domain of the chondrogenesis master regulator, Sox9 in complex with ChIP-Seq identified DNA element== | |
| - | + | <StructureSection load='4s2q' size='340' side='right'caption='[[4s2q]], [[Resolution|resolution]] 2.70Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4s2q]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4S2Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4S2Q FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4s2q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4s2q OCA], [https://pdbe.org/4s2q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4s2q RCSB], [https://www.ebi.ac.uk/pdbsum/4s2q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4s2q ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: Kolatkar | + | [https://www.uniprot.org/uniprot/SOX9_MOUSE SOX9_MOUSE] Plays an important role in the normal skeletal development. May regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes (By similarity). |
| - | [[Category: Moovarkumudalvan | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Synthetic construct]] | ||
| + | [[Category: Kolatkar PR]] | ||
| + | [[Category: Lescar J]] | ||
| + | [[Category: Moovarkumudalvan B]] | ||
| + | [[Category: Vivekanandan S]] | ||
Current revision
Crystal Structure of HMG domain of the chondrogenesis master regulator, Sox9 in complex with ChIP-Seq identified DNA element
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