This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4s3a

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (18:02, 20 September 2023) (edit) (undo)
 
(3 intermediate revisions not shown.)
Line 1: Line 1:
 +
==IspG in complex with Intermediate I==
==IspG in complex with Intermediate I==
-
<StructureSection load='4s3a' size='340' side='right' caption='[[4s3a]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
+
<StructureSection load='4s3a' size='340' side='right'caption='[[4s3a]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4s3a]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4S3A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4S3A FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4s3a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4S3A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4S3A FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=43Q:(3S)-1,3-DIHYDROXY-4-{[(S)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}-2-METHYLBUT-2-YLIUM,+CARBOKATION+INTERMEDIATE'>43Q</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
-
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=43Q:(3S)-1,3-DIHYDROXY-4-{[(S)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}-2-METHYLBUT-2-YLIUM,+CARBOKATION+INTERMEDIATE'>43Q</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4g9p|4g9p]], [[2y0f|2y0f]], [[3noy|3noy]], [[4s38|4s38]], [[4s39|4s39]], [[4s3b|4s3b]], [[4s3c|4s3c]], [[4s3d|4s3d]], [[4s3e|4s3e]], [[4s3f|4s3f]]</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4s3a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4s3a OCA], [https://pdbe.org/4s3a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4s3a RCSB], [https://www.ebi.ac.uk/pdbsum/4s3a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4s3a ProSAT]</span></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate_synthase (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.17.7.1 1.17.7.1] </span></td></tr>
+
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4s3a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4s3a OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4s3a RCSB], [http://www.ebi.ac.uk/pdbsum/4s3a PDBsum]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/ISPG_THET8 ISPG_THET8]] Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
+
[https://www.uniprot.org/uniprot/ISPG_THET8 ISPG_THET8] Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 19: Line 18:
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
 +
<div class="pdbe-citations 4s3a" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[IspG|IspG]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Abdel-Azeim, S]]
+
[[Category: Large Structures]]
-
[[Category: Bacher, A]]
+
[[Category: Thermus thermophilus HB8]]
-
[[Category: Dowd, B O]]
+
[[Category: Abdel-Azeim S]]
-
[[Category: Eppinger, J]]
+
[[Category: Bacher A]]
-
[[Category: Frank, A]]
+
[[Category: Eppinger J]]
-
[[Category: Groll, M]]
+
[[Category: Frank A]]
-
[[Category: Guerra, F]]
+
[[Category: Groll M]]
-
[[Category: Li, J]]
+
[[Category: Guerra F]]
-
[[Category: Oldfield, E]]
+
[[Category: Li J]]
-
[[Category: Quitterer, F]]
+
[[Category: O'Dowd B]]
-
[[Category: Rao, G]]
+
[[Category: Oldfield E]]
-
[[Category: Wang, K]]
+
[[Category: Quitterer F]]
-
[[Category: Drug development]]
+
[[Category: Rao G]]
-
[[Category: Iron-sulfur enzyme]]
+
[[Category: Wang K]]
-
[[Category: Methylerythritol-phosphate pathway]]
+
-
[[Category: Oxidoreductase]]
+
-
[[Category: Reaction mechanism]]
+
-
[[Category: Terpene biosynthesis]]
+

Current revision

IspG in complex with Intermediate I

PDB ID 4s3a

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4s3a"
Personal tools