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6s8m
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 6s8m is ON HOLD Authors: Moores, C.A., von Loeffelholz, O. Description: S. pombe microtubule decorated with Cut7 motor domain in the AMPPNP state [...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==S. pombe microtubule decorated with Cut7 motor domain in the AMPPNP state== | |
| + | <SX load='6s8m' size='340' side='right' viewer='molstar' caption='[[6s8m]], [[Resolution|resolution]] 4.50Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6s8m]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=5mlv 5mlv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6S8M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6S8M FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.5Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=EPB:7,11-DIHYDROXY-8,8,10,12,16-PENTAMETHYL-3-[1-METHYL-2-(2-METHYL-THIAZOL-4-YL)VINYL]-4,17-DIOXABICYCLO[14.1.0]HEPTADECANE-5,9-DIONE'>EPB</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6s8m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6s8m OCA], [https://pdbe.org/6s8m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6s8m RCSB], [https://www.ebi.ac.uk/pdbsum/6s8m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6s8m ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CUT7_SCHPO CUT7_SCHPO] Could be a spindle pole body motor. On transition from G2 to M phase of the cell cycle, the spindle pole body duplicates; the daughter pole bodies seed microtubules which interdigitate to form a short spindle that elongates to span the nucleus at metaphase. Mutations at cut7 block spindle formation. | ||
| - | + | ==See Also== | |
| - | + | *[[Kinesin 3D Structures|Kinesin 3D Structures]] | |
| - | + | *[[Tubulin 3D Structures|Tubulin 3D Structures]] | |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </SX> |
| - | [[Category: Moores | + | [[Category: Large Structures]] |
| + | [[Category: Schizosaccharomyces pombe]] | ||
| + | [[Category: Moores CA]] | ||
| + | [[Category: Von Loeffelholz O]] | ||
Current revision
S. pombe microtubule decorated with Cut7 motor domain in the AMPPNP state
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