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5ji1

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==Crystal Structure of GDF8==
==Crystal Structure of GDF8==
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<StructureSection load='5ji1' size='340' side='right' caption='[[5ji1]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
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<StructureSection load='5ji1' size='340' side='right'caption='[[5ji1]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5ji1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JI1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JI1 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5ji1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JI1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5JI1 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5jhw|5jhw]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Mstn, Gdf8 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ji1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ji1 OCA], [https://pdbe.org/5ji1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ji1 RCSB], [https://www.ebi.ac.uk/pdbsum/5ji1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ji1 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ji1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ji1 OCA], [http://pdbe.org/5ji1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ji1 RCSB], [http://www.ebi.ac.uk/pdbsum/5ji1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ji1 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/GDF8_MOUSE GDF8_MOUSE]] Acts specifically as a negative regulator of skeletal muscle growth.
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[https://www.uniprot.org/uniprot/GDF8_MOUSE GDF8_MOUSE] Acts specifically as a negative regulator of skeletal muscle growth.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5ji1" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5ji1" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Growth differentiation factor 3D STRUCTURES|Growth differentiation factor 3D STRUCTURES]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Lk3 transgenic mice]]
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[[Category: Large Structures]]
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[[Category: Thompson, T B]]
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[[Category: Mus musculus]]
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[[Category: Walker, R G]]
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[[Category: Thompson TB]]
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[[Category: Cytokine]]
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[[Category: Walker RG]]
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[[Category: Gdf8]]
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[[Category: Ligand]]
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[[Category: Myostatin]]
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[[Category: Tgfbeta]]
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Current revision

Crystal Structure of GDF8

PDB ID 5ji1

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