This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4txj

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:23, 27 September 2023) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
==Crystal structure of uridine phosphorylase from Schistosoma mansoni in complex with thymidine==
==Crystal structure of uridine phosphorylase from Schistosoma mansoni in complex with thymidine==
-
<StructureSection load='4txj' size='340' side='right' caption='[[4txj]], [[Resolution|resolution]] 1.66&Aring;' scene=''>
+
<StructureSection load='4txj' size='340' side='right'caption='[[4txj]], [[Resolution|resolution]] 1.66&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4txj]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TXJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4TXJ FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4txj]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Schistosoma_mansoni Schistosoma mansoni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TXJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4TXJ FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=THM:THYMIDINE'>THM</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.662&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4txh|4txh]], [[4txl|4txl]], [[4txm|4txm]], [[4txn|4txn]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=THM:THYMIDINE'>THM</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Uridine_phosphorylase Uridine phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.3 2.4.2.3] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4txj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4txj OCA], [https://pdbe.org/4txj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4txj RCSB], [https://www.ebi.ac.uk/pdbsum/4txj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4txj ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4txj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4txj OCA], [http://pdbe.org/4txj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4txj RCSB], [http://www.ebi.ac.uk/pdbsum/4txj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4txj ProSAT]</span></td></tr>
+
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/UPPA_SCHMA UPPA_SCHMA] Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate (PubMed:26898674). The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis (Probable).<ref>PMID:26898674</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 20: Line 21:
==See Also==
==See Also==
-
*[[Uridine phosphorylase|Uridine phosphorylase]]
+
*[[Uridine phosphorylase 3D structures|Uridine phosphorylase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Uridine phosphorylase]]
+
[[Category: Large Structures]]
-
[[Category: Brandao-Neto, J]]
+
[[Category: Schistosoma mansoni]]
-
[[Category: Cassago, A]]
+
[[Category: Brandao-Neto J]]
-
[[Category: DeMarco, R]]
+
[[Category: Cassago A]]
-
[[Category: Marinho, A]]
+
[[Category: DeMarco R]]
-
[[Category: Pereira, H M]]
+
[[Category: Marinho A]]
-
[[Category: Romanello, L]]
+
[[Category: Pereira HM]]
-
[[Category: Torini, J]]
+
[[Category: Romanello L]]
-
[[Category: Transferase]]
+
[[Category: Torini J]]
-
[[Category: Uridine phosphorylase thymidine]]
+

Current revision

Crystal structure of uridine phosphorylase from Schistosoma mansoni in complex with thymidine

PDB ID 4txj

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4txj"
Personal tools