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4txm
From Proteopedia
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==Crystal structure of uridine phosphorylase from Schistosoma mansoni in complex with thymine== | ==Crystal structure of uridine phosphorylase from Schistosoma mansoni in complex with thymine== | ||
| - | <StructureSection load='4txm' size='340' side='right' caption='[[4txm]], [[Resolution|resolution]] 1.93Å' scene=''> | + | <StructureSection load='4txm' size='340' side='right'caption='[[4txm]], [[Resolution|resolution]] 1.93Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4txm]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TXM OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[4txm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Schistosoma_mansoni Schistosoma mansoni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TXM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4TXM FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.93Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TDR:THYMINE'>TDR</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4txm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4txm OCA], [https://pdbe.org/4txm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4txm RCSB], [https://www.ebi.ac.uk/pdbsum/4txm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4txm ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/UPPA_SCHMA UPPA_SCHMA] Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate (PubMed:26898674). The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis (Probable).<ref>PMID:26898674</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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==See Also== | ==See Also== | ||
| - | *[[Uridine phosphorylase|Uridine phosphorylase]] | + | *[[Uridine phosphorylase 3D structures|Uridine phosphorylase 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Brandao-Neto | + | [[Category: Schistosoma mansoni]] |
| - | [[Category: Cassago | + | [[Category: Brandao-Neto J]] |
| - | [[Category: DeMarco | + | [[Category: Cassago A]] |
| - | [[Category: Marinho | + | [[Category: DeMarco R]] |
| - | [[Category: Pereira | + | [[Category: Marinho A]] |
| - | [[Category: Romanello | + | [[Category: Pereira HM]] |
| - | [[Category: Torini | + | [[Category: Romanello L]] |
| - | + | [[Category: Torini J]] | |
Current revision
Crystal structure of uridine phosphorylase from Schistosoma mansoni in complex with thymine
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