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4wcw

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==Ribosomal silencing factor during starvation or stationary phase (RsfS) from Mycobacterium tuberculosis==
==Ribosomal silencing factor during starvation or stationary phase (RsfS) from Mycobacterium tuberculosis==
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<StructureSection load='4wcw' size='340' side='right' caption='[[4wcw]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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<StructureSection load='4wcw' size='340' side='right'caption='[[4wcw]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4wcw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WCW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WCW FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4wcw]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WCW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WCW FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rsfS, Rv2420c, P425_02518, RVBD_2420c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wcw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wcw OCA], [http://pdbe.org/4wcw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wcw RCSB], [http://www.ebi.ac.uk/pdbsum/4wcw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4wcw ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4wcw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wcw OCA], [https://pdbe.org/4wcw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4wcw RCSB], [https://www.ebi.ac.uk/pdbsum/4wcw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4wcw ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/O86327_MYCTU O86327_MYCTU]] Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity).[HAMAP-Rule:MF_01477]
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[https://www.uniprot.org/uniprot/O86327_MYCTU O86327_MYCTU] Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity).[HAMAP-Rule:MF_01477]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Myctu]]
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[[Category: Large Structures]]
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[[Category: Hung, L]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Jiang, C]]
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[[Category: Hung L]]
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[[Category: Li, X]]
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[[Category: Jiang C]]
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[[Category: Sacchettini, J]]
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[[Category: Li X]]
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[[Category: Sun, Q]]
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[[Category: Sacchettini J]]
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[[Category: Structural genomic]]
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[[Category: Sun Q]]
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[[Category: Yang, K]]
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[[Category: Yang K]]
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[[Category: Zhang, J]]
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[[Category: Zhang J]]
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[[Category: Tbsgc]]
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[[Category: Translation]]
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[[Category: Tuberculosis ribosomal silencing dimer]]
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Current revision

Ribosomal silencing factor during starvation or stationary phase (RsfS) from Mycobacterium tuberculosis

PDB ID 4wcw

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