This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4wrw

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:35, 27 September 2023) (edit) (undo)
 
(One intermediate revision not shown.)
Line 1: Line 1:
==Crystal structure of Mycobacterium tuberculosis uracil-DNA glycosylase, Form IV==
==Crystal structure of Mycobacterium tuberculosis uracil-DNA glycosylase, Form IV==
-
<StructureSection load='4wrw' size='340' side='right' caption='[[4wrw]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
+
<StructureSection load='4wrw' size='340' side='right'caption='[[4wrw]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4wrw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WRW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WRW FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4wrw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WRW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WRW FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4wru|4wru]], [[4wrv|4wrv]], [[4wrx|4wrx]], [[4wry|4wry]], [[4wrz|4wrz]], [[4ws0|4ws0]], [[4ws1|4ws1]], [[4ws2|4ws2]], [[4ws3|4ws3]], [[4ws4|4ws4]], [[4ws5|4ws5]], [[4ws6|4ws6]], [[4ws7|4ws7]], [[4ws8|4ws8]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ung, Rv2976c, MTCY349.11 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4wrw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wrw OCA], [https://pdbe.org/4wrw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4wrw RCSB], [https://www.ebi.ac.uk/pdbsum/4wrw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4wrw ProSAT]</span></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Uracil-DNA_glycosylase Uracil-DNA glycosylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.27 3.2.2.27] </span></td></tr>
+
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wrw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wrw OCA], [http://pdbe.org/4wrw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wrw RCSB], [http://www.ebi.ac.uk/pdbsum/4wrw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4wrw ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/UNG_MYCTU UNG_MYCTU]] Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity).
+
[https://www.uniprot.org/uniprot/UNG_MYCTU UNG_MYCTU] Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 21: Line 19:
</div>
</div>
<div class="pdbe-citations 4wrw" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4wrw" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[DNA glycosylase 3D structures|DNA glycosylase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Myctu]]
+
[[Category: Large Structures]]
-
[[Category: Uracil-DNA glycosylase]]
+
[[Category: Mycobacterium tuberculosis H37Rv]]
-
[[Category: Arif, S M]]
+
[[Category: Arif SM]]
-
[[Category: Geethanandan, K]]
+
[[Category: Geethanandan K]]
-
[[Category: Mishra, P]]
+
[[Category: Mishra P]]
-
[[Category: Surolia, A]]
+
[[Category: Surolia A]]
-
[[Category: Varshney, U]]
+
[[Category: Varshney U]]
-
[[Category: Vijayan, M]]
+
[[Category: Vijayan M]]
-
[[Category: Conformational selection]]
+
-
[[Category: Dna-repair]]
+
-
[[Category: Excision repair]]
+
-
[[Category: Hydrolase]]
+
-
[[Category: Ligand-binding]]
+

Current revision

Crystal structure of Mycobacterium tuberculosis uracil-DNA glycosylase, Form IV

PDB ID 4wrw

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4wrw"
Personal tools