4xmb

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==Crystal structure of 2,2'-(naphthalene-1,4-diylbis(((4-methoxyphenyl)sulfonyl)azanediyl))diacetamide bound to human Keap1 Kelch domain==
==Crystal structure of 2,2'-(naphthalene-1,4-diylbis(((4-methoxyphenyl)sulfonyl)azanediyl))diacetamide bound to human Keap1 Kelch domain==
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<StructureSection load='4xmb' size='340' side='right' caption='[[4xmb]], [[Resolution|resolution]] 2.43&Aring;' scene=''>
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<StructureSection load='4xmb' size='340' side='right'caption='[[4xmb]], [[Resolution|resolution]] 2.43&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4xmb]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XMB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XMB FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4xmb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XMB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4XMB FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=41P:2,2-(NAPHTHALENE-1,4-DIYLBIS(((4-METHOXYPHENYL)SULFONYL)AZANEDIYL))DIACETAMIDE'>41P</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.428&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xmb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xmb OCA], [http://pdbe.org/4xmb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xmb RCSB], [http://www.ebi.ac.uk/pdbsum/4xmb PDBsum]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=41P:2,2-(NAPHTHALENE-1,4-DIYLBIS(((4-METHOXYPHENYL)SULFONYL)AZANEDIYL))DIACETAMIDE'>41P</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4xmb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xmb OCA], [https://pdbe.org/4xmb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4xmb RCSB], [https://www.ebi.ac.uk/pdbsum/4xmb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4xmb ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/KEAP1_HUMAN KEAP1_HUMAN]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 4xmb" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4xmb" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Kelch-like protein 3D structures|Kelch-like protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Luciano, J P]]
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[[Category: Homo sapiens]]
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[[Category: Mesecar, A D]]
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[[Category: Large Structures]]
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[[Category: Ryuzoji, A F]]
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[[Category: Luciano JP]]
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[[Category: Btb]]
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[[Category: Mesecar AD]]
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[[Category: Cul3]]
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[[Category: Ryuzoji AF]]
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[[Category: Cullin3]]
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[[Category: Nrf2 activator]]
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[[Category: Protein binding]]
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Current revision

Crystal structure of 2,2'-(naphthalene-1,4-diylbis(((4-methoxyphenyl)sulfonyl)azanediyl))diacetamide bound to human Keap1 Kelch domain

PDB ID 4xmb

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