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4xxd
From Proteopedia
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==Crystal Structure of mid-region amyloid beta capture by solanezumab== | ==Crystal Structure of mid-region amyloid beta capture by solanezumab== | ||
| - | <StructureSection load='4xxd' size='340' side='right' caption='[[4xxd]], [[Resolution|resolution]] 2.41Å' scene=''> | + | <StructureSection load='4xxd' size='340' side='right'caption='[[4xxd]], [[Resolution|resolution]] 2.41Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4xxd]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XXD OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[4xxd]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XXD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4XXD FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.41Å</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4xxd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xxd OCA], [https://pdbe.org/4xxd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4xxd RCSB], [https://www.ebi.ac.uk/pdbsum/4xxd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4xxd ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/IGKC_HUMAN IGKC_HUMAN] Defects in IGKC are the cause of immunoglobulin kappa light chain deficiency (IGKCD) [MIM:[https://omim.org/entry/614102 614102]. IGKCD is a disease characterized by the complete absence of immunoglobulin kappa chains.<ref>PMID:3931219</ref> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/IGKC_HUMAN IGKC_HUMAN] | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 4xxd" style="background-color:#fffaf0;"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Crespi GAN]] |
| - | [[Category: | + | [[Category: Hermans SJ]] |
| - | [[Category: | + | [[Category: Miles LA]] |
| - | [[Category: | + | [[Category: Parker MW]] |
| - | + | ||
Current revision
Crystal Structure of mid-region amyloid beta capture by solanezumab
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