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4y4f

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<StructureSection load='4y4f' size='340' side='right'caption='[[4y4f]], [[Resolution|resolution]] 3.19&Aring;' scene=''>
<StructureSection load='4y4f' size='340' side='right'caption='[[4y4f]], [[Resolution|resolution]] 3.19&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4y4f]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human] and [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y4F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Y4F FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4y4f]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y4F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Y4F FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=49M:(1R)-1,5-ANHYDRO-1-[(1E,3S,4S,5R)-4,5-DIHYDROXY-3-(NONACOSANOYLAMINO)NONADEC-1-EN-1-YL]-D-GALACTITOL'>49M</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.19&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4y2d|4y2d]], [[4y16|4y16]], [[4y4h|4y4h]], [[4y4k|4y4k]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=49M:(1R)-1,5-ANHYDRO-1-[(1E,3S,4S,5R)-4,5-DIHYDROXY-3-(NONACOSANOYLAMINO)NONADEC-1-EN-1-YL]-D-GALACTITOL'>49M</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Cd1d1, Cd1.1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice]), B2m ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice]), Trav11, Trav11d, HDCMA22P ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), TRBC2, TCRBC2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4y4f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y4f OCA], [https://pdbe.org/4y4f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4y4f RCSB], [https://www.ebi.ac.uk/pdbsum/4y4f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4y4f ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4y4f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y4f OCA], [http://pdbe.org/4y4f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4y4f RCSB], [http://www.ebi.ac.uk/pdbsum/4y4f PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4y4f ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CD1D1_MOUSE CD1D1_MOUSE]] Antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T-cells.<ref>PMID:11754812</ref> <ref>PMID:16314439</ref> <ref>PMID:16007091</ref> [[http://www.uniprot.org/uniprot/B2MG_MOUSE B2MG_MOUSE]] Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.
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[https://www.uniprot.org/uniprot/CD1D1_MOUSE CD1D1_MOUSE] Antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T-cells.<ref>PMID:11754812</ref> <ref>PMID:16314439</ref> <ref>PMID:16007091</ref>
==See Also==
==See Also==
*[[Beta-2 microglobulin 3D structures|Beta-2 microglobulin 3D structures]]
*[[Beta-2 microglobulin 3D structures|Beta-2 microglobulin 3D structures]]
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*[[T-cell receptor|T-cell receptor]]
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*[[T-cell receptor 3D structures|T-cell receptor 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Lk3 transgenic mice]]
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[[Category: Mus musculus]]
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[[Category: Yu, E D]]
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[[Category: Yu ED]]
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[[Category: Zajonc, D M]]
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[[Category: Zajonc DM]]
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[[Category: Glycolipid antigen presentation]]
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[[Category: Ig-fold]]
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[[Category: Immune system]]
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[[Category: Mhc-fold]]
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[[Category: T cell receptor]]
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Current revision

Crystal structure of the mCD1d/GCK127/iNKTCR ternary complex

PDB ID 4y4f

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