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4ykl

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==Hnt3 in complex with DNA and guanosine==
==Hnt3 in complex with DNA and guanosine==
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<StructureSection load='4ykl' size='340' side='right' caption='[[4ykl]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
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<StructureSection load='4ykl' size='340' side='right'caption='[[4ykl]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4ykl]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YKL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YKL FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4ykl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe_972h- Schizosaccharomyces pombe 972h-] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YKL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YKL FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GMP:GUANOSINE'>GMP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ykl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ykl OCA], [http://pdbe.org/4ykl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ykl RCSB], [http://www.ebi.ac.uk/pdbsum/4ykl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ykl ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GMP:GUANOSINE'>GMP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ykl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ykl OCA], [https://pdbe.org/4ykl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ykl RCSB], [https://www.ebi.ac.uk/pdbsum/4ykl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ykl ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/APTX_SCHPO APTX_SCHPO]] DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species. Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'-phosphate termini that can be efficiently rejoined (By similarity).
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[https://www.uniprot.org/uniprot/APTX_SCHPO APTX_SCHPO] DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species. Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'-phosphate termini that can be efficiently rejoined (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Chauleau, M]]
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[[Category: Large Structures]]
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[[Category: Jacewicz, A]]
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[[Category: Schizosaccharomyces pombe 972h-]]
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[[Category: Shuman, S]]
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[[Category: Synthetic construct]]
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[[Category: Gmp]]
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[[Category: Chauleau M]]
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[[Category: Hydrolase]]
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[[Category: Jacewicz A]]
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[[Category: Hydrolase-dna complex]]
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[[Category: Shuman S]]
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[[Category: Nucleotidyl transferase]]
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Current revision

Hnt3 in complex with DNA and guanosine

PDB ID 4ykl

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