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4yz6

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==Crystal Structure of Myc3[44-238] from Arabidopsis in complex with Jaz1 peptide [200-221]==
==Crystal Structure of Myc3[44-238] from Arabidopsis in complex with Jaz1 peptide [200-221]==
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<StructureSection load='4yz6' size='340' side='right' caption='[[4yz6]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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<StructureSection load='4yz6' size='340' side='right'caption='[[4yz6]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4yz6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YZ6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YZ6 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4yz6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YZ6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YZ6 FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4rru|4rru]], [[4rqw|4rqw]], [[4rs9|4rs9]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MYC3, ATR2, BHLH5, EN36, At5g46760, MZA15.18 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4yz6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yz6 OCA], [https://pdbe.org/4yz6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4yz6 RCSB], [https://www.ebi.ac.uk/pdbsum/4yz6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4yz6 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4yz6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yz6 OCA], [http://pdbe.org/4yz6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4yz6 RCSB], [http://www.ebi.ac.uk/pdbsum/4yz6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4yz6 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/MYC3_ARATH MYC3_ARATH]] Transcription factor involved in tryptophan, jasmonic acid (JA) and other stress-responsive gene regulation. With MYC2 and MYC4, controls additively subsets of JA-dependent responses. Can form complexes with all known glucosinolate-related MYBs to regulate glucosinolate biosynthesis. Binds to the G-box (5'-CACGTG-3') of promoters. Activates multiple TIFY/JAZ promoters.<ref>PMID:12136026</ref> <ref>PMID:21242320</ref> <ref>PMID:21321051</ref> <ref>PMID:21335373</ref> <ref>PMID:23943862</ref> [[http://www.uniprot.org/uniprot/TI10A_ARATH TI10A_ARATH]] Repressor of jasmonate responses negatively regulated by the proteasome in an SCF(COI1) E3 ubiquitin-protein ligase complex-dependent manner. Jasmonoyl-isoleucine (JA-Ile) specifically promotes COI1-TIFY10A/JAZ1 interaction. Interacts with COI1 and inositol pentakisphosphate to form a high-affinity jasmonates coreceptor.<ref>PMID:17637675</ref> <ref>PMID:17637677</ref> <ref>PMID:19151223</ref>
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[https://www.uniprot.org/uniprot/MYC3_ARATH MYC3_ARATH] Transcription factor involved in tryptophan, jasmonic acid (JA) and other stress-responsive gene regulation. With MYC2 and MYC4, controls additively subsets of JA-dependent responses. Can form complexes with all known glucosinolate-related MYBs to regulate glucosinolate biosynthesis. Binds to the G-box (5'-CACGTG-3') of promoters. Activates multiple TIFY/JAZ promoters.<ref>PMID:12136026</ref> <ref>PMID:21242320</ref> <ref>PMID:21321051</ref> <ref>PMID:21335373</ref> <ref>PMID:23943862</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Arath]]
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[[Category: Arabidopsis thaliana]]
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[[Category: Brunzelle, J]]
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[[Category: Large Structures]]
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[[Category: HE, S Y]]
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[[Category: Brunzelle J]]
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[[Category: Ke, J]]
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[[Category: HE SY]]
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[[Category: Melcher, K]]
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[[Category: Ke J]]
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[[Category: Xu, H E]]
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[[Category: Melcher K]]
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[[Category: Zhang, F]]
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[[Category: Xu HE]]
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[[Category: Jasmonate signaling pathway]]
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[[Category: Zhang F]]
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[[Category: Jaz1 repressor]]
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[[Category: Myc3 transcription factor]]
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[[Category: Plant transcriptional regulation]]
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[[Category: Transcription regulator]]
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Current revision

Crystal Structure of Myc3[44-238] from Arabidopsis in complex with Jaz1 peptide [200-221]

PDB ID 4yz6

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