This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4zy0

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:26, 27 September 2023) (edit) (undo)
 
(One intermediate revision not shown.)
Line 3: Line 3:
<StructureSection load='4zy0' size='340' side='right'caption='[[4zy0]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='4zy0' size='340' side='right'caption='[[4zy0]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4zy0]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Plafq Plafq]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZY0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZY0 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4zy0]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_FcB1/Columbia Plasmodium falciparum FcB1/Columbia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZY0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ZY0 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=4TM:N-{(1R)-2-(HYDROXYAMINO)-2-OXO-1-[4-(THIOPHEN-3-YL)PHENYL]ETHYL}-2,2-DIMETHYLPROPANAMIDE'>4TM</scene>, <scene name='pdbligand=CO3:CARBONATE+ION'>CO3</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3kqz|3kqz]], [[4zx8|4zx8]], [[4zx9|4zx9]], [[4zy1|4zy1]], [[4zy2|4zy2]], [[4zyq|4zyq]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=4TM:N-{(1R)-2-(HYDROXYAMINO)-2-OXO-1-[4-(THIOPHEN-3-YL)PHENYL]ETHYL}-2,2-DIMETHYLPROPANAMIDE'>4TM</scene>, <scene name='pdbligand=CO3:CARBONATE+ION'>CO3</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Leucyl_aminopeptidase Leucyl aminopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.1 3.4.11.1] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4zy0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zy0 OCA], [https://pdbe.org/4zy0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4zy0 RCSB], [https://www.ebi.ac.uk/pdbsum/4zy0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4zy0 ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zy0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zy0 OCA], [http://pdbe.org/4zy0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zy0 RCSB], [http://www.ebi.ac.uk/pdbsum/4zy0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4zy0 ProSAT]</span></td></tr>
+
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/A0A024V0B1_PLAFA A0A024V0B1_PLAFA]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 23: Line 24:
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Leucyl aminopeptidase]]
+
[[Category: Plasmodium falciparum FcB1/Columbia]]
-
[[Category: Plafq]]
+
[[Category: Drinkwater N]]
-
[[Category: Drinkwater, N]]
+
[[Category: McGowan S]]
-
[[Category: McGowan, S]]
+
-
[[Category: Hydrolase-hydrolase inhibitor complex]]
+
-
[[Category: Hydroxamic acid]]
+
-
[[Category: Inhibitor]]
+
-
[[Category: M17 leucyl-aminopeptidase]]
+
-
[[Category: Protease]]
+

Current revision

X-ray crystal structure of PfA-M17 in complex with hydroxamic acid-based inhibitor 10q

PDB ID 4zy0

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools