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5cu9
From Proteopedia
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<StructureSection load='5cu9' size='340' side='right'caption='[[5cu9]], [[Resolution|resolution]] 1.48Å' scene=''> | <StructureSection load='5cu9' size='340' side='right'caption='[[5cu9]], [[Resolution|resolution]] 1.48Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5cu9]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[5cu9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_albicans_SC5314 Candida albicans SC5314]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CU9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5CU9 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.48Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | <tr id=' | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5cu9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cu9 OCA], [https://pdbe.org/5cu9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5cu9 RCSB], [https://www.ebi.ac.uk/pdbsum/5cu9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5cu9 ProSAT]</span></td></tr> |
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| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/SOD5_CANAL SOD5_CANAL] Superoxide dismutases serve to convert damaging superoxide radicals, a key form of ROS, to less damaging hydrogen peroxide that can be converted into water by catalase action. Degrades host-derived reactive oxygen species to escape innate immune surveillance. Involved in the occurrence of miconazole-tolerant persisters in biofilms. Persisters are cells that survive high doses of an antimicrobial agent.<ref>PMID:14617819</ref> <ref>PMID:19019164</ref> <ref>PMID:21746956</ref> |
==See Also== | ==See Also== | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Candida albicans SC5314]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | + | [[Category: Galaleldeen A]] | |
| - | [[Category: Galaleldeen | + | [[Category: Hart PJ]] |
| - | [[Category: Hart | + | [[Category: Taylor AB]] |
| - | [[Category: Taylor | + | [[Category: Waninger-Saroni JJ]] |
| - | [[Category: Waninger-Saroni | + | |
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Current revision
CANDIDA ALBICANS SUPEROXIDE DISMUTASE 5 (SOD5), APO
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