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5cuq

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==Identification and characterization of novel broad spectrum inhibitors of the flavivirus methyltransferase==
==Identification and characterization of novel broad spectrum inhibitors of the flavivirus methyltransferase==
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<StructureSection load='5cuq' size='340' side='right' caption='[[5cuq]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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<StructureSection load='5cuq' size='340' side='right'caption='[[5cuq]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5cuq]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CUQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CUQ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5cuq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Dengue_virus_3 Dengue virus 3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CUQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5CUQ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NSC:N,N-BIS(4-AMINO-2-METHYLQUINOLIN-6-YL)UREA'>NSC</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.696&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cuq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cuq OCA], [http://pdbe.org/5cuq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5cuq RCSB], [http://www.ebi.ac.uk/pdbsum/5cuq PDBsum]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NSC:N,N-BIS(4-AMINO-2-METHYLQUINOLIN-6-YL)UREA'>NSC</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5cuq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cuq OCA], [https://pdbe.org/5cuq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5cuq RCSB], [https://www.ebi.ac.uk/pdbsum/5cuq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5cuq ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/C0LMU0_9FLAV C0LMU0_9FLAV]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5cuq" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5cuq" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Nonstructural protein 3D structures|Nonstructural protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Banavali, N K]]
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[[Category: Dengue virus 3]]
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[[Category: Brecher, B]]
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[[Category: Large Structures]]
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[[Category: Chen, H]]
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[[Category: Banavali NK]]
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[[Category: Jones, S A]]
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[[Category: Brecher B]]
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[[Category: Kramer, L D]]
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[[Category: Chen H]]
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[[Category: Li, H M]]
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[[Category: Jones SA]]
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[[Category: Li, Z]]
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[[Category: Kramer LD]]
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[[Category: Zhang, J]]
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[[Category: Li HM]]
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[[Category: Complex]]
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[[Category: Li Z]]
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[[Category: Dengue virus]]
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[[Category: Zhang J]]
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[[Category: Inhibitor]]
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[[Category: Methyltransferase]]
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[[Category: Viral protein-inhibitor complex]]
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Current revision

Identification and characterization of novel broad spectrum inhibitors of the flavivirus methyltransferase

PDB ID 5cuq

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