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5k3f

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==Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - His280Asn/Fluoroacetate - Cocrystallized - Single Protomer Reacted with Ligand==
==Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - His280Asn/Fluoroacetate - Cocrystallized - Single Protomer Reacted with Ligand==
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<StructureSection load='5k3f' size='340' side='right' caption='[[5k3f]], [[Resolution|resolution]] 1.54&Aring;' scene=''>
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<StructureSection load='5k3f' size='340' side='right'caption='[[5k3f]], [[Resolution|resolution]] 1.54&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5k3f]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5K3F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5K3F FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5k3f]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodopseudomonas_palustris_CGA009 Rhodopseudomonas palustris CGA009]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5K3F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5K3F FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.54&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ASB:ASPARTIC+ACID-4-CARBOXYMETHYL+ESTER'>ASB</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ASB:ASPARTIC+ACID-4-CARBOXYMETHYL+ESTER'>ASB</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5k3b|5k3b]], [[5k3a|5k3a]], [[5k3c|5k3c]], [[5k3d|5k3d]], [[5k3e|5k3e]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5k3f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5k3f OCA], [https://pdbe.org/5k3f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5k3f RCSB], [https://www.ebi.ac.uk/pdbsum/5k3f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5k3f ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Haloacetate_dehalogenase Haloacetate dehalogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.8.1.3 3.8.1.3] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5k3f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5k3f OCA], [http://pdbe.org/5k3f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5k3f RCSB], [http://www.ebi.ac.uk/pdbsum/5k3f PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5k3f ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/DEHA_RHOPA DEHA_RHOPA]] Catalyzes the hydrolytic defluorination of fluoroacetate to produce glycolate. Has lower activity towards bromoacetate and chloroacetate.<ref>PMID:21510690</ref> <ref>PMID:21510690</ref>
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[https://www.uniprot.org/uniprot/DEHA_RHOPA DEHA_RHOPA] Catalyzes the hydrolytic defluorination of fluoroacetate to produce glycolate. Has lower activity towards bromoacetate and chloroacetate.<ref>PMID:21510690</ref> <ref>PMID:21510690</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5k3f" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5k3f" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Dehalogenase 3D structures|Dehalogenase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Haloacetate dehalogenase]]
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[[Category: Large Structures]]
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[[Category: Kim, T H]]
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[[Category: Rhodopseudomonas palustris CGA009]]
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[[Category: Mehrabi, P]]
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[[Category: Kim TH]]
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[[Category: Pai, E F]]
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[[Category: Mehrabi P]]
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[[Category: Prosser, S R]]
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[[Category: Pai EF]]
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[[Category: Dehalogenase]]
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[[Category: Prosser SR]]
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[[Category: Homodimer]]
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[[Category: Hydrolase]]
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Current revision

Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - His280Asn/Fluoroacetate - Cocrystallized - Single Protomer Reacted with Ligand

PDB ID 5k3f

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