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5km8

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==Human Histidine Triad Nucleotide Binding Protein 2 (hHint2) Cidofovir complex==
==Human Histidine Triad Nucleotide Binding Protein 2 (hHint2) Cidofovir complex==
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<StructureSection load='5km8' size='340' side='right' caption='[[5km8]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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<StructureSection load='5km8' size='340' side='right'caption='[[5km8]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5km8]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KM8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5KM8 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5km8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KM8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5KM8 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=L8P:({[(2S)-1-(4-AMINO-2-OXOPYRIMIDIN-1(2H)-YL)-3-HYDROXYPROPAN-2-YL]OXY}METHYL)PHOSPHONIC+ACID'>L8P</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3tw2|3tw2]], [[5ipb|5ipb]], [[5ipc|5ipc]], [[5ipd|5ipd]], [[5ipe|5ipe]], [[5kly|5kly]], [[5klz|5klz]], [[5km0|5km0]], [[5km1|5km1]], [[5km2|5km2]], [[5km3|5km3]], [[5km4|5km4]], [[5km5|5km5]], [[5km6|5km6]], [[5km7|5km7]], [[5km9|5km9]], [[5kma|5kma]], [[5kmb|5kmb]], [[5kmc|5kmc]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=L8P:({[(2S)-1-(4-AMINO-2-OXOPYRIMIDIN-1(2H)-YL)-3-HYDROXYPROPAN-2-YL]OXY}METHYL)PHOSPHONIC+ACID'>L8P</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5km8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5km8 OCA], [http://pdbe.org/5km8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5km8 RCSB], [http://www.ebi.ac.uk/pdbsum/5km8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5km8 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5km8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5km8 OCA], [https://pdbe.org/5km8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5km8 RCSB], [https://www.ebi.ac.uk/pdbsum/5km8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5km8 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/HINT2_HUMAN HINT2_HUMAN]] Hydrolase probably involved in steroid biosynthesis. May play a role in apoptosis. Has adenosine phosphoramidase activity.<ref>PMID:16762638</ref> <ref>PMID:18653718</ref>
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[https://www.uniprot.org/uniprot/HINT2_HUMAN HINT2_HUMAN] Hydrolase probably involved in steroid biosynthesis. May play a role in apoptosis. Has adenosine phosphoramidase activity.<ref>PMID:16762638</ref> <ref>PMID:18653718</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5km8" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5km8" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Histidine triad nucleotide-binding protein 3D structures|Histidine triad nucleotide-binding protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Finzel, B C]]
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[[Category: Homo sapiens]]
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[[Category: Maize, K M]]
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[[Category: Large Structures]]
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[[Category: Hint]]
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[[Category: Finzel BC]]
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[[Category: Histidine triad]]
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[[Category: Maize KM]]
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[[Category: Hit]]
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[[Category: Hydrolase]]
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Current revision

Human Histidine Triad Nucleotide Binding Protein 2 (hHint2) Cidofovir complex

PDB ID 5km8

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