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3aex

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==Catalytic intermediate analogue of threonine synthase from Thermus thermophilus HB8==
==Catalytic intermediate analogue of threonine synthase from Thermus thermophilus HB8==
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<StructureSection load='3aex' size='340' side='right' caption='[[3aex]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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<StructureSection load='3aex' size='340' side='right'caption='[[3aex]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3aex]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AEX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3AEX FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3aex]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AEX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AEX FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AN7:(3E)-4-{3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}-2-OXOBUT-3-ENOIC+ACID'>AN7</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1uim|1uim]], [[1uin|1uin]], [[1v7c|1v7c]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AN7:(3E)-4-{3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}-2-OXOBUT-3-ENOIC+ACID'>AN7</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TTHA0491 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=274 Thermus thermophilus])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3aex FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3aex OCA], [https://pdbe.org/3aex PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3aex RCSB], [https://www.ebi.ac.uk/pdbsum/3aex PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3aex ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Threonine_synthase Threonine synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.3.1 4.2.3.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3aex FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3aex OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3aex RCSB], [http://www.ebi.ac.uk/pdbsum/3aex PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/Q5SL02_THET8 Q5SL02_THET8]] Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.[PIRNR:PIRNR038945]
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[https://www.uniprot.org/uniprot/Q5SL02_THET8 Q5SL02_THET8] Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.[PIRNR:PIRNR038945]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3aex" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Thermus thermophilus]]
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[[Category: Large Structures]]
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[[Category: Threonine synthase]]
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[[Category: Thermus thermophilus HB8]]
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[[Category: Hayashi, H]]
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[[Category: Hayashi H]]
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[[Category: Machida, Y]]
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[[Category: Machida Y]]
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[[Category: Murakawa, T]]
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[[Category: Murakawa T]]
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[[Category: Lyase]]
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[[Category: Plp]]
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[[Category: Pyridoxal phosphate]]
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Current revision

Catalytic intermediate analogue of threonine synthase from Thermus thermophilus HB8

PDB ID 3aex

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