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5tnj

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==Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted 4-Vinyl-1-cyclohexene 1,2-epoxide hydrolysis intermediate==
==Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted 4-Vinyl-1-cyclohexene 1,2-epoxide hydrolysis intermediate==
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<StructureSection load='5tnj' size='340' side='right' caption='[[5tnj]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
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<StructureSection load='5tnj' size='340' side='right'caption='[[5tnj]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5tnj]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TNJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TNJ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5tnj]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_UCBPP-PA14 Pseudomonas aeruginosa UCBPP-PA14]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TNJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5TNJ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8MD:(1S,2S,4S)-4-ethenylcyclohexane-1,2-diol'>8MD</scene>, <scene name='pdbligand=AVH:(1R,2R,4R)-4-ethenylcyclohexane-1,2-diol'>AVH</scene>, <scene name='pdbligand=BVH:(1R,2R,4S)-4-ethenylcyclohexane-1,2-diol'>BVH</scene>, <scene name='pdbligand=DVH:(1S,2S,4R)-4-ethenylcyclohexane-1,2-diol'>DVH</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3kd2|3kd2]], [[4dmc|4dmc]], [[5tnd|5tnd]], [[5tnf|5tnf]], [[5tng|5tng]], [[5tnh|5tnh]], [[5tni|5tni]], [[5tnk|5tnk]], [[5tnl|5tnl]], [[5tnm|5tnm]], [[5tnn|5tnn]], [[5tnp|5tnp]], [[5tnq|5tnq]], [[5tnr|5tnr]], [[5tns|5tns]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8MD:(1S,2S,4S)-4-ethenylcyclohexane-1,2-diol'>8MD</scene>, <scene name='pdbligand=AVH:(1R,2R,4R)-4-ethenylcyclohexane-1,2-diol'>AVH</scene>, <scene name='pdbligand=BVH:(1R,2R,4S)-4-ethenylcyclohexane-1,2-diol'>BVH</scene>, <scene name='pdbligand=DVH:(1S,2S,4R)-4-ethenylcyclohexane-1,2-diol'>DVH</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5tnj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tnj OCA], [http://pdbe.org/5tnj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5tnj RCSB], [http://www.ebi.ac.uk/pdbsum/5tnj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5tnj ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5tnj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tnj OCA], [https://pdbe.org/5tnj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5tnj RCSB], [https://www.ebi.ac.uk/pdbsum/5tnj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5tnj ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/A0A0H2ZD27_PSEAB A0A0H2ZD27_PSEAB]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5tnj" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5tnj" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[CFTR inhibitory factor|CFTR inhibitory factor]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Hvorecny, K L]]
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[[Category: Large Structures]]
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[[Category: Madden, D R]]
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[[Category: Pseudomonas aeruginosa UCBPP-PA14]]
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[[Category: Epoxide hydrolase]]
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[[Category: Hvorecny KL]]
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[[Category: Hydrolase]]
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[[Category: Madden DR]]
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[[Category: Hydroxyalkyl-enzyme intermediate]]
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Current revision

Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted 4-Vinyl-1-cyclohexene 1,2-epoxide hydrolysis intermediate

PDB ID 5tnj

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