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5ts2

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==Crystal structure of a phosphopantetheine adenylyltransferase (CoaD, PPAT) from Pseudomonas aeruginosa bound to dephospho coenzyme A==
==Crystal structure of a phosphopantetheine adenylyltransferase (CoaD, PPAT) from Pseudomonas aeruginosa bound to dephospho coenzyme A==
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<StructureSection load='5ts2' size='340' side='right' caption='[[5ts2]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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<StructureSection load='5ts2' size='340' side='right'caption='[[5ts2]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5ts2]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TS2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TS2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5ts2]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_LESB58 Pseudomonas aeruginosa LESB58]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TS2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5TS2 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=COD:DEPHOSPHO+COENZYME+A'>COD</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pantetheine-phosphate_adenylyltransferase Pantetheine-phosphate adenylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.3 2.7.7.3] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=COD:DEPHOSPHO+COENZYME+A'>COD</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ts2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ts2 OCA], [http://pdbe.org/5ts2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ts2 RCSB], [http://www.ebi.ac.uk/pdbsum/5ts2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ts2 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ts2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ts2 OCA], [https://pdbe.org/5ts2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ts2 RCSB], [https://www.ebi.ac.uk/pdbsum/5ts2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ts2 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/COAD_PSEA8 COAD_PSEA8]] Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
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[https://www.uniprot.org/uniprot/COAD_PSEAE COAD_PSEAE] Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Pantetheine-phosphate adenylyltransferase]]
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[[Category: Large Structures]]
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[[Category: Structural genomic]]
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[[Category: Pseudomonas aeruginosa LESB58]]
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[[Category: Coad]]
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[[Category: Coenzyme a biosynthesis]]
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[[Category: Ppat]]
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[[Category: Ssgcid]]
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[[Category: Transferase]]
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Current revision

Crystal structure of a phosphopantetheine adenylyltransferase (CoaD, PPAT) from Pseudomonas aeruginosa bound to dephospho coenzyme A

PDB ID 5ts2

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