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5us2

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Current revision (13:33, 4 October 2023) (edit) (undo)
 
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<StructureSection load='5us2' size='340' side='right'caption='[[5us2]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='5us2' size='340' side='right'caption='[[5us2]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5us2]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Bachd Bachd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5US2 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5US2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5us2]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Alkalihalobacillus_halodurans_C-125 Alkalihalobacillus halodurans C-125] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5US2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5US2 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=US3:1-(2-DEOXY-5-O-PHOSPHONO-BETA-D-ERYTHRO-PENTOFURANOSYL)-5-METHYL-2-SELANYLPYRIMIDIN-4(1H)-ONE'>US3</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=US3:1-(2-DEOXY-5-O-PHOSPHONO-BETA-D-ERYTHRO-PENTOFURANOSYL)-5-METHYL-2-SELANYLPYRIMIDIN-4(1H)-ONE'>US3</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5usa|5usa]], [[5use|5use]], [[5usg|5usg]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5us2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5us2 OCA], [https://pdbe.org/5us2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5us2 RCSB], [https://www.ebi.ac.uk/pdbsum/5us2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5us2 ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rnhA, BH0863 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=272558 BACHD])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ribonuclease_H Ribonuclease H], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.26.4 3.1.26.4] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5us2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5us2 OCA], [http://pdbe.org/5us2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5us2 RCSB], [http://www.ebi.ac.uk/pdbsum/5us2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5us2 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RNH1_BACHD RNH1_BACHD]] Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
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[https://www.uniprot.org/uniprot/RNH1_HALH5 RNH1_HALH5] Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.<ref>PMID:15989951</ref>
==See Also==
==See Also==
*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bachd]]
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[[Category: Alkalihalobacillus halodurans C-125]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Ribonuclease H]]
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[[Category: Synthetic construct]]
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[[Category: Fang, Z]]
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[[Category: Fang Z]]
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[[Category: Huang, Z]]
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[[Category: Huang Z]]
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[[Category: Yang, F]]
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[[Category: Yang F]]
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[[Category: Hydrolase - rna - dna complex]]
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Current revision

2-Se-T2-DNA and native RNA hybrid in complex with RNase H catalytic domain D132N mutant

PDB ID 5us2

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