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5v2i
From Proteopedia
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==Crystal structure of a mutant glycosylasparaginase (G172D) that causes the genetic disease Aspartylglucosaminuria== | ==Crystal structure of a mutant glycosylasparaginase (G172D) that causes the genetic disease Aspartylglucosaminuria== | ||
| - | <StructureSection load='5v2i' size='340' side='right' caption='[[5v2i]], [[Resolution|resolution]] 1.83Å' scene=''> | + | <StructureSection load='5v2i' size='340' side='right'caption='[[5v2i]], [[Resolution|resolution]] 1.83Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5v2i]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[5v2i]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Elizabethkingia_meningoseptica Elizabethkingia meningoseptica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V2I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5V2I FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.83Å</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5v2i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5v2i OCA], [https://pdbe.org/5v2i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5v2i RCSB], [https://www.ebi.ac.uk/pdbsum/5v2i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5v2i ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ASPG_ELIMR ASPG_ELIMR] Cleaves the GlcNAc-Asn bond which joins oligosaccharides to the peptide of asparagine-linked glycoproteins. Requires that the glycosylated asparagine moiety is not substituted on its N-(R1) and C- (R2) terminus. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</div> | </div> | ||
<div class="pdbe-citations 5v2i" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5v2i" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Asparaginase 3D structures|Asparaginase 3D structures]] | ||
| + | *[[Glycosylasparaginase|Glycosylasparaginase]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Elizabethkingia meningoseptica]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Guo H]] |
| - | [[Category: | + | [[Category: Pande S]] |
| - | + | ||
| - | + | ||
Current revision
Crystal structure of a mutant glycosylasparaginase (G172D) that causes the genetic disease Aspartylglucosaminuria
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