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5vnx

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Current revision (13:52, 4 October 2023) (edit) (undo)
 
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<StructureSection load='5vnx' size='340' side='right'caption='[[5vnx]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
<StructureSection load='5vnx' size='340' side='right'caption='[[5vnx]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5vnx]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Burm1 Burm1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VNX OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5VNX FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5vnx]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Burkholderia_multivorans_ATCC_17616 Burkholderia multivorans ATCC 17616]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VNX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5VNX FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BEN:BENZAMIDINE'>BEN</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=9EV:6-[(2R)-2-{3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}-5-OXO-1,3-OXAZOLIDIN-3-YL]-L-NORLEUCINE'>9EV</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9EV:6-[(2R)-2-{3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}-5-OXO-1,3-OXAZOLIDIN-3-YL]-L-NORLEUCINE'>9EV</scene>, <scene name='pdbligand=BEN:BENZAMIDINE'>BEN</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">bioF, Bmul_0373, BMULJ_02881 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=395019 BURM1])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5vnx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vnx OCA], [https://pdbe.org/5vnx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5vnx RCSB], [https://www.ebi.ac.uk/pdbsum/5vnx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5vnx ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.47 2.3.1.47] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5vnx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vnx OCA], [http://pdbe.org/5vnx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5vnx RCSB], [http://www.ebi.ac.uk/pdbsum/5vnx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5vnx ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/BIOF_BURM1 BIOF_BURM1]] Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
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[https://www.uniprot.org/uniprot/BIOF_BURM1 BIOF_BURM1] Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Burm1]]
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[[Category: Burkholderia multivorans ATCC 17616]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Transferase]]
 
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[[Category: Structural genomic]]
 
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[[Category: 8-amino-7-oxononanoate synthase]]
 
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[[Category: Burkholderia multivoran]]
 
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[[Category: Ssgcid]]
 

Current revision

Crystal structure of an 8-amino-7-oxononanoate synthase from Burkholderia multivorans with a potential glycine-PLP-Lys242 cyclized intermediate or byproduct

PDB ID 5vnx

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