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6awe
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==Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with 2-fluoro-6-(2-pyridin-2-ylethylamino)benzonitrile== | ==Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with 2-fluoro-6-(2-pyridin-2-ylethylamino)benzonitrile== | ||
| - | <StructureSection load='6awe' size='340' side='right' caption='[[6awe]], [[Resolution|resolution]] 1.65Å' scene=''> | + | <StructureSection load='6awe' size='340' side='right'caption='[[6awe]], [[Resolution|resolution]] 1.65Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[6awe]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AWE OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[6awe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Schistosoma_mansoni Schistosoma mansoni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AWE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6AWE FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C0J:2-fluoro-6-{[2-(pyridin-2-yl)ethyl]amino}benzonitrile'>C0J</scene>, <scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6awe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6awe OCA], [https://pdbe.org/6awe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6awe RCSB], [https://www.ebi.ac.uk/pdbsum/6awe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6awe ProSAT]</span></td></tr> | |
| - | + | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/A0A0U3AGT1_SCHMA A0A0U3AGT1_SCHMA] The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.[PIRNR:PIRNR000477] |
| + | |||
| + | ==See Also== | ||
| + | *[[Purine nucleoside phosphorylase 3D structures|Purine nucleoside phosphorylase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Barbosa | + | [[Category: Schistosoma mansoni]] |
| - | [[Category: Bird | + | [[Category: Barbosa JARG]] |
| - | [[Category: Collins | + | [[Category: Bird L]] |
| - | [[Category: Delft | + | [[Category: Collins P]] |
| - | [[Category: Faheem | + | [[Category: Delft FV]] |
| - | [[Category: Neto | + | [[Category: Faheem M]] |
| - | [[Category: Pearce | + | [[Category: Neto JB]] |
| - | [[Category: Pereira | + | [[Category: Pearce NM]] |
| - | [[Category: Valadares | + | [[Category: Pereira HM]] |
| - | + | [[Category: Valadares NF]] | |
| - | + | ||
Current revision
Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with 2-fluoro-6-(2-pyridin-2-ylethylamino)benzonitrile
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Categories: Large Structures | Schistosoma mansoni | Barbosa JARG | Bird L | Collins P | Delft FV | Faheem M | Neto JB | Pearce NM | Pereira HM | Valadares NF
