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6b2u

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Current revision (14:31, 4 October 2023) (edit) (undo)
 
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<StructureSection load='6b2u' size='340' side='right'caption='[[6b2u]], [[Resolution|resolution]] 2.04&Aring;' scene=''>
<StructureSection load='6b2u' size='340' side='right'caption='[[6b2u]], [[Resolution|resolution]] 2.04&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6b2u]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Xancp Xancp]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B2U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6B2U FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6b2u]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Xanthomonas_campestris_pv._campestris_str._ATCC_33913 Xanthomonas campestris pv. campestris str. ATCC 33913]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B2U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6B2U FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CER:(2S,+3R)-3-HYDROXY-4-OXO-7,10-TRANS,TRANS-DODECADIENAMIDE'>CER</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.04&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">fabH, XCC0212 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=190485 XANCP])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CER:(2S,+3R)-3-HYDROXY-4-OXO-7,10-TRANS,TRANS-DODECADIENAMIDE'>CER</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6b2u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6b2u OCA], [http://pdbe.org/6b2u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6b2u RCSB], [http://www.ebi.ac.uk/pdbsum/6b2u PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6b2u ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6b2u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6b2u OCA], [https://pdbe.org/6b2u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6b2u RCSB], [https://www.ebi.ac.uk/pdbsum/6b2u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6b2u ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/OLEA_XANCP OLEA_XANCP] Involved in olefin biosynthesis (PubMed:21266575, PubMed:22524624, PubMed:27815501, PubMed:28223313). Catalyzes a non-decarboxylative head-to-head Claisen condensation of two acyl-CoA molecules, generating an (R)-2-alkyl-3-oxoalkanoate (PubMed:21266575, PubMed:22524624, PubMed:27815501). Is active with fatty acyl-CoA substrates that ranged from C(8) to C(16) in length, and is the most active with palmitoyl-CoA and myristoyl-CoA (PubMed:21266575).<ref>PMID:21266575</ref> <ref>PMID:22524624</ref> <ref>PMID:27815501</ref> <ref>PMID:28223313</ref>
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==See Also==
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*[[Acyl carrier protein synthase 3D structures|Acyl carrier protein synthase 3D structures]]
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Xancp]]
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[[Category: Xanthomonas campestris pv. campestris str. ATCC 33913]]
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[[Category: Christenson, J K]]
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[[Category: Christenson JK]]
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[[Category: Esler, M A]]
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[[Category: Esler MA]]
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[[Category: Goblirsch, B R]]
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[[Category: Goblirsch BR]]
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[[Category: Jensen, M R]]
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[[Category: Jensen MR]]
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[[Category: Mohamed, F A]]
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[[Category: Mohamed FA]]
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[[Category: Wackett, L P]]
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[[Category: Wackett LP]]
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[[Category: Wilmot, C M]]
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[[Category: Wilmot CM]]
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[[Category: Cerulenin]]
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[[Category: Condensation]]
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[[Category: Olea]]
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[[Category: Thiolase]]
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[[Category: Transferase]]
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Current revision

Crystal structure of Xanthomonas campestris OleA H285N with Cerulenin

PDB ID 6b2u

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