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6b6k
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with 6-methyl-2,3-dihydropyridazin-3-one== | |
| + | <StructureSection load='6b6k' size='340' side='right'caption='[[6b6k]], [[Resolution|resolution]] 1.46Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6b6k]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Schistosoma_mansoni Schistosoma mansoni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B6K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6B6K FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.46Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene>, <scene name='pdbligand=CVG:6-methylpyridazin-3-ol'>CVG</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6b6k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6b6k OCA], [https://pdbe.org/6b6k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6b6k RCSB], [https://www.ebi.ac.uk/pdbsum/6b6k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6b6k ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/A0A0U3AGT1_SCHMA A0A0U3AGT1_SCHMA] The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.[PIRNR:PIRNR000477] | ||
| - | + | ==See Also== | |
| - | + | *[[Purine nucleoside phosphorylase 3D structures|Purine nucleoside phosphorylase 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Schistosoma mansoni]] |
| - | [[Category: | + | [[Category: Barbosa JARG]] |
| - | [[Category: | + | [[Category: Bird L]] |
| - | [[Category: | + | [[Category: Collins P]] |
| - | [[Category: Faheem | + | [[Category: Delft FV]] |
| - | [[Category: | + | [[Category: Faheem M]] |
| - | [[Category: | + | [[Category: Neto JB]] |
| - | [[Category: Valadares | + | [[Category: Pearce NM]] |
| + | [[Category: Pereira HM]] | ||
| + | [[Category: Valadares NF]] | ||
Current revision
Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with 6-methyl-2,3-dihydropyridazin-3-one
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Categories: Large Structures | Schistosoma mansoni | Barbosa JARG | Bird L | Collins P | Delft FV | Faheem M | Neto JB | Pearce NM | Pereira HM | Valadares NF
