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6bhb

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Current revision (14:40, 4 October 2023) (edit) (undo)
 
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<StructureSection load='6bhb' size='340' side='right'caption='[[6bhb]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='6bhb' size='340' side='right'caption='[[6bhb]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6bhb]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BHB OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6BHB FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6bhb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Schistosoma_mansoni Schistosoma mansoni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BHB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6BHB FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=DS1:2-aminopyrimidin-5-ol'>DS1</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=DS1:2-aminopyrimidin-5-ol'>DS1</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5cxq|5cxq]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6bhb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bhb OCA], [https://pdbe.org/6bhb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6bhb RCSB], [https://www.ebi.ac.uk/pdbsum/6bhb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6bhb ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Purine-nucleoside_phosphorylase Purine-nucleoside phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.1 2.4.2.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6bhb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bhb OCA], [http://pdbe.org/6bhb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bhb RCSB], [http://www.ebi.ac.uk/pdbsum/6bhb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bhb ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/A0A0U3AGT1_SCHMA A0A0U3AGT1_SCHMA]] The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.[PIRNR:PIRNR000477]
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[https://www.uniprot.org/uniprot/A0A0U3AGT1_SCHMA A0A0U3AGT1_SCHMA] The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.[PIRNR:PIRNR000477]
==See Also==
==See Also==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Purine-nucleoside phosphorylase]]
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[[Category: Schistosoma mansoni]]
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[[Category: Barbosa, J A.R G]]
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[[Category: Barbosa JARG]]
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[[Category: Bird, L]]
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[[Category: Bird L]]
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[[Category: Collins, P]]
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[[Category: Collins P]]
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[[Category: Delft, F V]]
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[[Category: Delft FV]]
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[[Category: Faheem, M]]
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[[Category: Faheem M]]
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[[Category: Neto, J B]]
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[[Category: Neto JB]]
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[[Category: Pearce, N M]]
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[[Category: Pearce NM]]
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[[Category: Pereira, H M]]
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[[Category: Pereira HM]]
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[[Category: Valadares, N F]]
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[[Category: Valadares NF]]
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[[Category: Purine nucleoside phosphorylase]]
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[[Category: Transferase]]
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Current revision

Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with 2-aminopyrimidin-5-ol

PDB ID 6bhb

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