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6br5

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==N2 neuraminidase in complex with a novel antiviral compound==
==N2 neuraminidase in complex with a novel antiviral compound==
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<StructureSection load='6br5' size='340' side='right' caption='[[6br5]], [[Resolution|resolution]] 2.04&Aring;' scene=''>
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<StructureSection load='6br5' size='340' side='right'caption='[[6br5]], [[Resolution|resolution]] 2.04&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6br5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Influenza_a_virus_(a/new_york/20342/2010(h3n2)) Influenza a virus (a/new york/20342/2010(h3n2))]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BR5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BR5 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6br5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Influenza_A_virus_(A/Perth/16/2009(H3N2)) Influenza A virus (A/Perth/16/2009(H3N2))]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BR5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6BR5 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=GYG:(1R)-4-(acetylamino)-1,5-anhydro-3-carbamimidamido-2,3,4-trideoxy-1-sulfo-D-glycero-D-galacto-octitol'>GYG</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.0379076&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=869376 Influenza A virus (A/New York/20342/2010(H3N2))])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=GYG:(1R)-4-acetamido-1,5-anhydro-3-carbamimidamido-2,3,4-trideoxy-1-sulfo-D-glycero-D-galacto-octitol'>GYG</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Exo-alpha-sialidase Exo-alpha-sialidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.18 3.2.1.18] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6br5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6br5 OCA], [https://pdbe.org/6br5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6br5 RCSB], [https://www.ebi.ac.uk/pdbsum/6br5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6br5 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6br5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6br5 OCA], [http://pdbe.org/6br5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6br5 RCSB], [http://www.ebi.ac.uk/pdbsum/6br5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6br5 ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/E0UY46_9INFA E0UY46_9INFA]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6br5" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6br5" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Neuraminidase 3D structures|Neuraminidase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Exo-alpha-sialidase]]
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[[Category: Large Structures]]
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[[Category: Bailly, B]]
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[[Category: Bailly B]]
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[[Category: Gao, G F]]
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[[Category: Gao GF]]
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[[Category: Hadhazi, A]]
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[[Category: Hadhazi A]]
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[[Category: Itzstein, M von]]
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[[Category: Li LH]]
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[[Category: Li, L H]]
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[[Category: Pascolutti M]]
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[[Category: Pascolutti, M]]
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[[Category: Thomson RJ]]
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[[Category: Thomson, R J]]
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[[Category: Ve T]]
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[[Category: Ve, T]]
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[[Category: Von Itzstein M]]
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[[Category: Complex]]
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[[Category: Hydrolase]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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Current revision

N2 neuraminidase in complex with a novel antiviral compound

PDB ID 6br5

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