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6c43

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Current revision (14:55, 4 October 2023) (edit) (undo)
 
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<StructureSection load='6c43' size='340' side='right'caption='[[6c43]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
<StructureSection load='6c43' size='340' side='right'caption='[[6c43]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6c43]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6C43 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6C43 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6c43]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica Salmonella enterica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6C43 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6C43 FirstGlance]. <br>
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</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aminobutyraldehyde_dehydrogenase Aminobutyraldehyde dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.19 1.2.1.19] </span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6c43 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6c43 OCA], [http://pdbe.org/6c43 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6c43 RCSB], [http://www.ebi.ac.uk/pdbsum/6c43 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6c43 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6c43 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6c43 OCA], [https://pdbe.org/6c43 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6c43 RCSB], [https://www.ebi.ac.uk/pdbsum/6c43 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6c43 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/A0A0W3SL32_SALCE A0A0W3SL32_SALCE]] Catalyzes the oxidation of 1-pyrroline, which is spontaneously formed from 4-aminobutanal, leading to 4-aminobutanoate (GABA).[HAMAP-Rule:MF_01275]
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[https://www.uniprot.org/uniprot/ABDH_SALTY ABDH_SALTY] Catalyzes the oxidation 4-aminobutanal (gamma-aminobutyraldehyde) to 4-aminobutanoate (gamma-aminobutyrate or GABA). This is the second step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate via 4-aminobutanal. Also functions as a 5-aminopentanal dehydrogenase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.[HAMAP-Rule:MF_01275]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Aminobutyraldehyde dehydrogenase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Anderson, W F]]
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[[Category: Salmonella enterica]]
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[[Category: Structural genomic]]
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[[Category: Anderson WF]]
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[[Category: Dubrovska, I]]
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[[Category: Dubrovska I]]
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[[Category: Joachimiak, A]]
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[[Category: Joachimiak A]]
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[[Category: Kwon, K]]
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[[Category: Kwon K]]
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[[Category: Minasov, G]]
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[[Category: Minasov G]]
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[[Category: Satchell, K J.F]]
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[[Category: Satchell KJF]]
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[[Category: Shuvalova, L]]
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[[Category: Shuvalova L]]
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[[Category: Tekleab, H]]
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[[Category: Tekleab H]]
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[[Category: Winsor, J]]
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[[Category: Winsor J]]
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[[Category: Csgid]]
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[[Category: Gamma-aminobutyraldehyde dehydrogenase]]
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[[Category: Oxidoreductase]]
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[[Category: Ribosomal protein]]
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Current revision

2.9 Angstrom Resolution Crystal Structure of Gamma-Aminobutyraldehyde Dehydrogenase from Salmonella typhimurium.

PDB ID 6c43

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