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6c5f

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Current revision (14:56, 4 October 2023) (edit) (undo)
 
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==Human D-Dopachrome tautomerase (D-DT)/ macrophage migration inhibitory factor 2 (MIF2) complexed with the selective inhibitor 4-CPPC==
==Human D-Dopachrome tautomerase (D-DT)/ macrophage migration inhibitory factor 2 (MIF2) complexed with the selective inhibitor 4-CPPC==
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<StructureSection load='6c5f' size='340' side='right' caption='[[6c5f]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
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<StructureSection load='6c5f' size='340' side='right'caption='[[6c5f]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6c5f]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6C5F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6C5F FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6c5f]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6C5F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6C5F FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7L9:4-(3-carboxyphenyl)pyridine-2,5-dicarboxylic+acid'>7L9</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DDT ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7L9:4-(3-carboxyphenyl)pyridine-2,5-dicarboxylic+acid'>7L9</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/D-dopachrome_decarboxylase D-dopachrome decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.84 4.1.1.84] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6c5f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6c5f OCA], [https://pdbe.org/6c5f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6c5f RCSB], [https://www.ebi.ac.uk/pdbsum/6c5f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6c5f ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6c5f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6c5f OCA], [http://pdbe.org/6c5f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6c5f RCSB], [http://www.ebi.ac.uk/pdbsum/6c5f PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6c5f ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/DOPD_HUMAN DOPD_HUMAN]] Tautomerization of D-dopachrome with decarboxylation to give 5,6-dihydroxyindole (DHI).
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[https://www.uniprot.org/uniprot/DOPD_HUMAN DOPD_HUMAN] Tautomerization of D-dopachrome with decarboxylation to give 5,6-dihydroxyindole (DHI).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6c5f" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6c5f" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Macrophage inhibitory factor 3D structures|Macrophage inhibitory factor 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: D-dopachrome decarboxylase]]
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[[Category: Homo sapiens]]
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[[Category: Human]]
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[[Category: Large Structures]]
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[[Category: Lolis, E J]]
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[[Category: Lolis EJ]]
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[[Category: Pantouris, G]]
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[[Category: Pantouris G]]
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[[Category: Cytokine]]
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[[Category: Selective inhibitor]]
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Current revision

Human D-Dopachrome tautomerase (D-DT)/ macrophage migration inhibitory factor 2 (MIF2) complexed with the selective inhibitor 4-CPPC

PDB ID 6c5f

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