6c7z

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==Crystal structure of the Q108K:K40L:T51V:R58F mutant of human Cellular Retinol Binding Protein II in complex with synthetic Ligand Julolidine==
==Crystal structure of the Q108K:K40L:T51V:R58F mutant of human Cellular Retinol Binding Protein II in complex with synthetic Ligand Julolidine==
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<StructureSection load='6c7z' size='340' side='right' caption='[[6c7z]], [[Resolution|resolution]] 1.42&Aring;' scene=''>
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<StructureSection load='6c7z' size='340' side='right'caption='[[6c7z]], [[Resolution|resolution]] 1.42&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6c7z]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6C7Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6C7Z FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6c7z]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6C7Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6C7Z FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=JLO:(2E,4E)-3-methyl-5-(2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinolin-9-yl)penta-2,4-dienal'>JLO</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.42&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5f58|5f58]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=JLO:(2E,4E)-3-methyl-5-(2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinolin-9-yl)penta-2,4-dienal'>JLO</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6c7z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6c7z OCA], [http://pdbe.org/6c7z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6c7z RCSB], [http://www.ebi.ac.uk/pdbsum/6c7z PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6c7z ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6c7z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6c7z OCA], [https://pdbe.org/6c7z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6c7z RCSB], [https://www.ebi.ac.uk/pdbsum/6c7z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6c7z ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RET2_HUMAN RET2_HUMAN]] Intracellular transport of retinol.
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[https://www.uniprot.org/uniprot/RET2_HUMAN RET2_HUMAN] Intracellular transport of retinol.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6c7z" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6c7z" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Retinol-binding protein 3D structures|Retinol-binding protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Geiger, J H]]
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[[Category: Homo sapiens]]
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[[Category: Nosrati, M]]
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[[Category: Large Structures]]
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[[Category: Hcrbpii]]
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[[Category: Geiger JH]]
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[[Category: Protein engineering]]
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[[Category: Nosrati M]]
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[[Category: Ratiometric ph probe]]
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[[Category: Transport protein]]
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Current revision

Crystal structure of the Q108K:K40L:T51V:R58F mutant of human Cellular Retinol Binding Protein II in complex with synthetic Ligand Julolidine

PDB ID 6c7z

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