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6cme

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Current revision (15:07, 4 October 2023) (edit) (undo)
 
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<StructureSection load='6cme' size='340' side='right'caption='[[6cme]], [[Resolution|resolution]] 1.92&Aring;' scene=''>
<StructureSection load='6cme' size='340' side='right'caption='[[6cme]], [[Resolution|resolution]] 1.92&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6cme]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CME OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6CME FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6cme]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CME OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6CME FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.92&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3mmk|3mmk]], [[2rgt|2rgt]], [[2jtn|2jtn]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Isl2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6cme FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cme OCA], [https://pdbe.org/6cme PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6cme RCSB], [https://www.ebi.ac.uk/pdbsum/6cme PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6cme ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6cme FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cme OCA], [http://pdbe.org/6cme PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6cme RCSB], [http://www.ebi.ac.uk/pdbsum/6cme PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6cme ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/LHX4_MOUSE LHX4_MOUSE]] May play a critical role in the development of respiratory control mechanisms and in the normal growth and maturation of the lung.
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[https://www.uniprot.org/uniprot/LHX4_MOUSE LHX4_MOUSE] May play a critical role in the development of respiratory control mechanisms and in the normal growth and maturation of the lung.[https://www.uniprot.org/uniprot/ISL2_MOUSE ISL2_MOUSE] Transcriptional factor that defines subclasses of motoneurons that segregate into columns in the spinal cord and select distinct axon pathways.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Lk3 transgenic mice]]
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[[Category: Mus musculus]]
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[[Category: Guss, J M]]
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[[Category: Guss JM]]
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[[Category: Matthews, J M]]
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[[Category: Matthews JM]]
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[[Category: Silva, A]]
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[[Category: Silva A]]
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[[Category: Stokes, P H]]
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[[Category: Stokes PH]]
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[[Category: Cell-type specification]]
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[[Category: Lim-homeodomain]]
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[[Category: Neural development]]
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[[Category: Transcription]]
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Current revision

Structure of wild-type ISL2-LID in complex with LHX4-LIM1+2

PDB ID 6cme

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