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5lb5

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==Crystal structure of human RECQL5 helicase in complex with ADP/Mg (tricilinc form).==
==Crystal structure of human RECQL5 helicase in complex with ADP/Mg (tricilinc form).==
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<StructureSection load='5lb5' size='340' side='right' caption='[[5lb5]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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<StructureSection load='5lb5' size='340' side='right'caption='[[5lb5]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5lb5]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LB5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LB5 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5lb5]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LB5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5LB5 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RECQL5, RECQ5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_helicase DNA helicase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.12 3.6.4.12] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5lb5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lb5 OCA], [https://pdbe.org/5lb5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5lb5 RCSB], [https://www.ebi.ac.uk/pdbsum/5lb5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5lb5 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5lb5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lb5 OCA], [http://pdbe.org/5lb5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5lb5 RCSB], [http://www.ebi.ac.uk/pdbsum/5lb5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5lb5 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RECQ5_HUMAN RECQ5_HUMAN]] May have an important role in DNA metabolism.
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[https://www.uniprot.org/uniprot/RECQ5_HUMAN RECQ5_HUMAN] May have an important role in DNA metabolism.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5lb5" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5lb5" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Helicase 3D structures|Helicase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: DNA helicase]]
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[[Category: Homo sapiens]]
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[[Category: Human]]
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[[Category: Large Structures]]
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[[Category: Aitkenhead, H]]
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[[Category: Aitkenhead H]]
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[[Category: Arrowsmith, C H]]
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[[Category: Arrowsmith CH]]
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[[Category: Bountra, C]]
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[[Category: Bountra C]]
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[[Category: Delft, F Von]]
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[[Category: Edwards AM]]
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[[Category: Edwards, A M]]
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[[Category: Gileadi O]]
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[[Category: Gileadi, O]]
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[[Category: Krojer T]]
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[[Category: Krojer, T]]
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[[Category: Newman JA]]
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[[Category: Newman, J A]]
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[[Category: Savitsky P]]
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[[Category: Structural genomic]]
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[[Category: Von Delft F]]
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[[Category: Savitsky, P]]
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[[Category: Dna repair]]
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[[Category: Helicase]]
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[[Category: Hydrolase]]
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[[Category: Recq]]
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[[Category: Sgc]]
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[[Category: Transcription]]
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Current revision

Crystal structure of human RECQL5 helicase in complex with ADP/Mg (tricilinc form).

PDB ID 5lb5

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