This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


8ucx

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
(New page: '''Unreleased structure''' The entry 8ucx is ON HOLD Authors: Fried, S.D.E., Boxer, S.G. Description: Dihydrofolate Reductase Complexed with Folate Category: Unreleased Structures ...)
Current revision (06:01, 11 October 2023) (edit) (undo)
 
(One intermediate revision not shown.)
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 8ucx is ON HOLD
+
==Dihydrofolate Reductase Complexed with Folate==
-
 
+
<StructureSection load='8ucx' size='340' side='right'caption='[[8ucx]], [[Resolution|resolution]] 1.57&Aring;' scene=''>
-
Authors: Fried, S.D.E., Boxer, S.G.
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[8ucx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8UCX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8UCX FirstGlance]. <br>
-
Description: Dihydrofolate Reductase Complexed with Folate
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.57&#8491;</td></tr>
-
[[Category: Unreleased Structures]]
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FOL:FOLIC+ACID'>FOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=OCS:CYSTEINESULFONIC+ACID'>OCS</scene></td></tr>
-
[[Category: Fried, S.D.E]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ucx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ucx OCA], [https://pdbe.org/8ucx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ucx RCSB], [https://www.ebi.ac.uk/pdbsum/8ucx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ucx ProSAT]</span></td></tr>
-
[[Category: Boxer, S.G]]
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/C3TR70_ECOLX C3TR70_ECOLX] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).[PIRNR:PIRNR000194]
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Escherichia coli]]
 +
[[Category: Large Structures]]
 +
[[Category: Boxer SG]]
 +
[[Category: Fried SDE]]

Current revision

Dihydrofolate Reductase Complexed with Folate

PDB ID 8ucx

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools