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5xe9

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==Crystal Structure of the Complex of the Peptidase Domain of Streptococcus mutans ComA with a Small Molecule Inhibitor.==
==Crystal Structure of the Complex of the Peptidase Domain of Streptococcus mutans ComA with a Small Molecule Inhibitor.==
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<StructureSection load='5xe9' size='340' side='right' caption='[[5xe9]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
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<StructureSection load='5xe9' size='340' side='right'caption='[[5xe9]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5xe9]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XE9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5XE9 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5xe9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_mutans_UA159 Streptococcus mutans UA159]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XE9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5XE9 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6CH:[(1~{S},2~{R},4~{S},5~{R})-5-[5-(4-methoxyphenyl)-2-methyl-pyrazol-3-yl]-1-azabicyclo[2.2.2]octan-2-yl]methyl+~{N}-propylcarbamate'>6CH</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.101&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5xe8|5xe8]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6CH:[(1~{S},2~{R},4~{S},5~{R})-5-[5-(4-methoxyphenyl)-2-methyl-pyrazol-3-yl]-1-azabicyclo[2.2.2]octan-2-yl]methyl+~{N}-propylcarbamate'>6CH</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5xe9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xe9 OCA], [http://pdbe.org/5xe9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xe9 RCSB], [http://www.ebi.ac.uk/pdbsum/5xe9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xe9 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5xe9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xe9 OCA], [https://pdbe.org/5xe9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5xe9 RCSB], [https://www.ebi.ac.uk/pdbsum/5xe9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5xe9 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q8DW05_STRMU Q8DW05_STRMU]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Beniyama, Y]]
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[[Category: Large Structures]]
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[[Category: Fukui, K]]
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[[Category: Streptococcus mutans UA159]]
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[[Category: Fukuyama, T]]
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[[Category: Beniyama Y]]
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[[Category: Ishii, S]]
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[[Category: Fukui K]]
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[[Category: Kodama, T]]
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[[Category: Fukuyama T]]
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[[Category: Kojima, H]]
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[[Category: Ishii S]]
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[[Category: Kumagai, K]]
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[[Category: Kodama T]]
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[[Category: Nagano, T]]
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[[Category: Kojima H]]
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[[Category: Okabe, T]]
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[[Category: Kumagai K]]
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[[Category: Yano, T]]
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[[Category: Nagano T]]
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[[Category: Yokoshima, S]]
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[[Category: Okabe T]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Yano T]]
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[[Category: Peptidase]]
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[[Category: Yokoshima S]]

Current revision

Crystal Structure of the Complex of the Peptidase Domain of Streptococcus mutans ComA with a Small Molecule Inhibitor.

PDB ID 5xe9

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