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6dis
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of HCV NS3/4A protease in complex with P4-1 (AJ-71)== | |
| + | <StructureSection load='6dis' size='340' side='right'caption='[[6dis]], [[Resolution|resolution]] 1.92Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6dis]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Hepacivirus_C Hepacivirus C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DIS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6DIS FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.921Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GKG:1,1,1-trifluoro-2-methylpropan-2-yl+[(2R,6S,12Z,13aS,14aR,16aS)-2-[(7-methoxy-3-methylquinoxalin-2-yl)oxy]-14a-{[(1-methylcyclopropyl)sulfonyl]carbamoyl}-5,+16-dioxo-1,2,3,5,6,7,8,9,10,11,13a,14,14a,15,16,16a-hexadecahydrocyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecin-6-+yl]carbamate'>GKG</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6dis FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dis OCA], [https://pdbe.org/6dis PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6dis RCSB], [https://www.ebi.ac.uk/pdbsum/6dis PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6dis ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/A0A0B4WYC6_9HEPC A0A0B4WYC6_9HEPC] | ||
| - | + | ==See Also== | |
| - | + | *[[Virus protease 3D structures|Virus protease 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: Matthew | + | [[Category: Hepacivirus C]] |
| - | [[Category: Schiffer | + | [[Category: Large Structures]] |
| + | [[Category: Matthew AN]] | ||
| + | [[Category: Schiffer CA]] | ||
Current revision
Crystal structure of HCV NS3/4A protease in complex with P4-1 (AJ-71)
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